Results 31 to 40 of about 187,466 (308)
Frontiers in Cardiovascular Medicine, 2019 Although exercise derived activation of Nrf2 signaling augments myocardial antioxidant signaling, the molecular mechanisms underlying the benefits of moderate exercise training (MET) in the heart remain elusive.
Gobinath Shanmugam +9 more
doaj +1 more source
Metabolic and redox signaling in the retina [PDF]
Cellular and Molecular Life Sciences, 2016 Visual perception by photoreceptors relies on the interaction of incident photons from light with a derivative of vitamin A that is covalently linked to an opsin molecule located in a special subcellular structure, the photoreceptor outer segment.
Léveillard, Thierry, Sahel, José-Alain
openaire +4 more sources
A biphasic effect of TNF-α in regulation of the Keap1/Nrf2 pathway in cardiomyocytes
Redox Biology, 2016 Antagonizing TNF-α signaling attenuates chronic inflammatory disease, but is associated with adverse effects on the cardiovascular system. Therefore the impact of TNF-α on basal control of redox signaling events needs to be understand in more depth. This
Gobinath Shanmugam +9 more
doaj +1 more source
The Aging Liver: Redox Biology and Liver Regeneration
, 2021 Significance: During aging, excessive production of reactive species in the liver leads to redox imbalance with consequent oxidative damage and impaired organ homeostasis.
Vendemiale, Gianluigi +1 more
core +1 more source
Adipokines and redox signaling: impact on fatty liver disease. [PDF]
, 2011 Adipokines (adipose tissue cytokines) are polypeptide factors secreted by adipose tissue in a highly regulated manner. The 'classical' adipokines (leptin, adiponectin, and resistin) are expressed only by adipocytes, but other adipokines have been shown ...
Marra, Fabio. +2 more
core +1 more source
Sex differences in redox homeostasis in renal disease
Redox Biology, 2020 Sex differences in redox signaling in the kidney present new challenges and opportunities for understanding the physiology and pathophysiology of the kidney.
Tanecia Mitchell +2 more
doaj +1 more source
Dynamic Redox Regulation of IL-4 Signaling. [PDF]
PLoS Computational Biology, 2015 Quantifying the magnitude and dynamics of protein oxidation during cell signaling is technically challenging. Computational modeling provides tractable, quantitative methods to test hypotheses of redox mechanisms that may be simultaneously operative ...
Gaurav Dwivedi +3 more
doaj +1 more source
Redox regulation of the NPR1-TGA1 system of Arabidopsis thaliana by nitric oxide [PDF]
, 2010 The role of reactive oxygen and nitrogen species in local and systemic defense reactions is well documented. NPR1 and TGA1 are key redox-controlled regulators of systemic acquired resistance in plants. NPR1 monomers interact with the reduced form of TGA1,
Bernd Müller +14 more
core +1 more source
Redox‐dependent signal transduction [PDF]
FEBS Letters, 2000 Reactive oxygen species (ROS) such as superoxide anions and hydrogen peroxide appear to be transiently produced in response to growth factor and cytokine stimulation. A variety of evidence suggests that this ligand‐stimulated change in the cellular redox state participates in downstream signal transduction.
openaire +2 more sources
Constitutive activation of Nrf2 induces a stable reductive state in the mouse myocardium
Redox Biology, 2017 Redox homeostasis regulates key cellular signaling pathways in both physiology and pathology. The cell's antioxidant response provides a defense against oxidative stress and establishes a redox tone permissive for cell signaling. The molecular regulation
Gobinath Shanmugam +4 more
doaj +1 more source