Results 201 to 210 of about 2,311,393 (299)

Identifying Suitable Reference Gene Candidates for Quantification of DNA Damage-Induced Cellular Responses in Human U2OS Cell Culture System. [PDF]

Biomolecules, 2023
Barta N, Ördög N, Pantazi V, Berzsenyi I, Borsos BN, Majoros H, Páhi ZG, Ujfaludi Z, Pankotai T.   +8 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

qPCR-Based Reference Gene Validation in <i>Canarium album</i>: Stability Across Varieties and Developmental Stages. [PDF]

Curr Issues Mol Biol
Zhao Q, Jiang L, Luo W, Wang W, Shen C, Ye Q, Chen Q, Xie Q.   +7 more
europepmc   +1 more source

Identification of RNU44 as an Endogenous Reference Gene for Normalizing Cell-Free RNA in Tuberculosis. [PDF]

Open Forum Infect Dis, 2022
Gu W, Tu X, Lu W, Yin Y, Meng Q, Wang X, Zhang F, Fu Y.   +7 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Identification of SnRNA U6 as an endogenous reference gene for normalization of MiRNA expression data in COVID-19 patients. [PDF]

Sci Rep
de Santana Silva ÍTS, Fehlberg HF, Ferreira FB, da Silva MF, Dos Santos PR, Porto VM, Dias JCT, Albuquerque GR, Mariano APM, Gadelha SR, Kaneto CM.   +10 more
europepmc   +1 more source

Reference Gene Selection for qPCR Analysis in Schima superba under Abiotic Stress. [PDF]

Genes (Basel), 2022
Yao J, Zhu G, Liang D, He B, Wang Y, Cai Y, Zhang Q.   +6 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Evaluation of Suitable Reference Gene During the Development of Paired or Unpaired Female <i>Schistosoma japonicum</i> on the 18th and the 23rd Days Post Infection. [PDF]

Pathogens
Wang S, Feng L, Sun J.
europepmc   +1 more source

Validation of reference gene stability for miRNA quantification by reverse transcription quantitative PCR in the peripheral blood of patients with COVID-19 critical illness. [PDF]

PLoS One, 2023
Formosa A, Acton E, Lee A, Turgeon P, Izhar S, Plant P, Tsoporis JN, Soussi S, Trahtemberg U, Baker A, Dos Santos CC.   +10 more
europepmc   +1 more source