Results 31 to 40 of about 13,061,353 (246)

Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function

Science, 2022
Understanding gene function and regulation in homeostasis and disease requires knowledge of the cellular and tissue contexts in which genes are expressed.
Gökçen Eraslan, Eugene Drokhlyansky, Shankara K. Anand, Evgenij Fiskin, Ayshwarya Subramanian, M. Slyper, Jiali Wang, Nicholas Van Wittenberghe, J. Rouhana, Julia Waldman, O. Ashenberg, M. Lek, Danielle Dionne, Thet Su Win, Michael S. Cuoco, Olena Kuksenko, A. Tsankov, P. Branton, Jamie L. Marshall, A. Greka, G. Getz, A. Segrè, F. Aguet, O. Rozenblatt-Rosen, K. Ardlie, A. Regev   +25 more
semanticscholar   +1 more source

Visualizing Viral Infection In Vivo by Multi-Photon Intravital Microscopy

Viruses, 2018
Viral pathogens have adapted to the host organism to exploit the cellular machinery for virus replication and to modulate the host cells for efficient systemic dissemination and immune evasion.
Xaver Sewald
doaj   +1 more source

Using RNA-Seq to Identify Reference Genes of the Transition from Brown to White Adipose Tissue in Goats

Animals, 2020
Brown adipose tissues have unique non-shivering thermogenesis functions, can be found in newborn ruminate animals, and then are gradually replaced by white adipose tissues in adulthood.
Linjie Wang, Xingyue Chen, Tianzeng Song, Xujia Zhang, Siyuan Zhan, Jiaxue Cao, Tao Zhong, Jiazhong Guo, Li Li, Hongping Zhang, Yan Wang   +10 more
doaj   +1 more source

The Douglas-Fir Genome Sequence Reveals Specialization of the Photosynthetic Apparatus in Pinaceae. [PDF]

, 2017
A reference genome sequence for Pseudotsuga menziesii var. menziesii (Mirb.) Franco (Coastal Douglas-fir) is reported, thus providing a reference sequence for a third genus of the family Pinaceae.
Cardeno, Charis, Casola, Claudio, Crepeau, Marc W, Cronn, Richard, Gonzalez-Ibeas, Daniel, Holt, Carson, Koralewski, Tomasz E, Langley, Charles H, McGuire, Patrick E, Neale, David B, Paul, Robin, Pertea, Geo M, Puiu, Daniela, Salzberg, Steven L, Sezen, U Uzay, Stevens, Kristian A, Wegrzyn, Jill L, Wheeler, Nicholas C, Yandell, Mark, Yorke, James A, Zaman, Sumaira, Zimin, Aleksey V   +21 more
core   +2 more sources

KEGG as a reference resource for gene and protein annotation

Nucleic Acids Res., 2015
KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an integrated database resource for biological interpretation of genome sequences and other high-throughput data.
M. Kanehisa, Yoko Sato, Masayuki Kawashima, Miho Furumichi, M. Tanabe   +4 more
semanticscholar   +1 more source

Reference gene selection and RNA preservation protocol in the cat flea, Ctenocephalides felis, for gene expression studies [PDF]

, 2016
This work was supported by a Knowledge Transfer Network BBSRC Industrial Case (#414 BB/L502467/1) studentship in association Zoetis Inc.Peer ...
Baird, John, Bowman, Alan S, Campbell, Ewan M, McIntosh, Catriona H, Woods, Debra J., Zinser, Erich   +5 more
core   +1 more source

Optimal use of statistical methods to validate reference gene stability in longitudinal studies

bioRxiv, 2019
Multiple statistical approaches have been proposed to validate reference genes in qPCR assays. However, conflicting results from these statistical methods pose a major hurdle in the choice of the best reference genes.
V. Sundaram, N. Sampathkumar, C. Massaad, Julien Grenier   +3 more
semanticscholar   +1 more source

Efficient Protein Expression and Virus-Induced Gene Silencing in Plants Using a Crinivirus-Derived Vector. [PDF]

, 2018
Plant virus-based vectors are valuable tools for recombinant gene expression and functional genomics for both basic and applied research. In this study, Lettuce infectious yellows virus (LIYV) of the genus Crinivirus was engineered into a virus vector ...
Falk, Bryce W, Qiao, Wenjie
core   +3 more sources

Reliable reference genes and abiotic stress marker genes in Klebsormidium nitens

Scientific Reports, 2022
AbstractMicroalgae have recently emerged as a key research topic, especially as biological models. Among them, the green alga Klebsormidium nitens, thanks to its particular adaptation to environmental stresses, represents an interesting photosynthetic eukaryote for studying the transition stages leading to the colonization of terrestrial life.
Chatelain, Pauline, Blanchard, Cécile, Astier, Jeremy, Klinguer, Agnès, Wendehenne, David, Jeandroz, Sylvain, Rosnoblet, Claire   +6 more
openaire   +5 more sources

Identification of miR-16 as an endogenous reference gene for the normalization of urinary exosomal miRNA expression data from CKD patients

PLoS ONE, 2017
Chronic kidney disease (CKD) is a severe disorder with an increasing incidence worldwide. An early detection may help to prevent its progression and to minimize the risk of cardiovascular diseases as one of the major comorbidities.
Tim Lange, S. Stracke, R. Rettig, U. Lendeckel, Jana Kuhn, R. Schlüter, V. Rippe, K. Endlich, N. Endlich   +8 more
semanticscholar   +1 more source