Conserved noncoding sequences highlight shared components of regulatory networks in dicotyledonous plants [PDF]
, 2012 Conserved noncoding sequences (CNSs) in DNA are reliable pointers to regulatory elements controlling gene expression. Using a comparative genomics approach with four dicotyledonous plant species (Arabidopsis thaliana, papaya [Carica papaya], poplar ...
Barrington, Christopher +11 more
core +2 more sources
Dissecting sources of quantitative gene expression pattern divergence between Drosophila species
Molecular Systems Biology, 2012 Gene expression patterns can diverge between species due to changes in a gene's regulatory DNA or changes in the proteins, e.g., transcription factors (TFs), that regulate the gene.
Zeba Wunderlich +5 more
doaj +1 more source
Repetitive Elements in Mycoplasma hyopneumoniae Transcriptional Regulation. [PDF]
PLoS ONE, 2016 Transcriptional regulation, a multiple-step process, is still poorly understood in the important pig pathogen Mycoplasma hyopneumoniae. Basic motifs like promoters and terminators have already been described, but no other cis-regulatory elements have ...
Amanda Malvessi Cattani +3 more
doaj +1 more source
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP [PDF]
, 2013 Through controlling the nuclear level of active positive transcription elongation factor b (P-TEFb), the 7SK small nuclear RNA (snRNA) functions as a key regulator of RNA polymerase II transcription.
Bayfield +43 more
core +3 more sources
Transcription factor trapping by RNA in gene regulatory elements [PDF]
Science, 2015 Noncoding RNA helps protein binding Besides reading the coding regions of genes, RNA polymerase generates RNA at promoter-proximal and -distal DNA elements, but the function of these molecules is largely unknown. Sigova et al.
Sigova, A. A. +9 more
openaire +3 more sources
Evolution of UCP1 Transcriptional Regulatory Elements Across the Mammalian Phylogeny
Frontiers in Physiology, 2017 Uncoupling protein 1 (UCP1) permits non-shivering thermogenesis (NST) when highly expressed in brown adipose tissue (BAT) mitochondria. Exclusive to placental mammals, BAT has commonly been regarded to be advantageous for thermoregulation in hibernators,
Michael J. Gaudry, Kevin L. Campbell
doaj +1 more source
Transcriptional regulatory elements of the RAS2 gene of Saccharomyces cerevisiae [PDF]
Nucleic Acids Research, 1990 We have analyzed a series of 5' deletions of the RAS2 gene to investigate its complex transcriptional regulation in the yeast Saccharomyces cerevisiae. Two positive transcriptional regulatory elements were identified. Element A regulates two of the three clusters of RAS2 transcripts.
Lisziewicz J +6 more
openaire +3 more sources
Molecular Systems Biology, 2010 Systems biology seeks a genomic‐level interpretation of transcriptional regulatory information represented by patterns of protein‐binding sites. Obtaining this information without direct experimentation is challenging; minor alterations in binding sites ...
Walid D Fakhouri +5 more
doaj +1 more source
TRED: a Transcriptional Regulatory Element Database and a platform for in silico gene regulation studies [PDF]
, 2005 In order to understand gene regulation, accurate and comprehensive knowledge of transcriptional regulatory elements is essential. Here, we report our efforts in building a mammalian Transcriptional Regulatory Element Database (TRED) with associated data ...
Zhao, F. +3 more
core +2 more sources
Enhancer RNAs in transcriptional regulation: recent insights
Frontiers in Cell and Developmental Biology, 2023 Enhancers are a class of cis-regulatory elements in the genome that instruct the spatiotemporal transcriptional program. Last decade has witnessed an exploration of non-coding transcripts pervasively transcribed from active enhancers in diverse contexts,
Qi Chen +6 more
doaj +1 more source