Results 141 to 150 of about 885,465 (288)

Relative Biological Effectiveness [PDF]

, 2020
openaire   +1 more source

Proton linear energy transfer and variable relative biological effectiveness for adolescent patients with Hodgkin lymphoma. [PDF]

BJR Open, 2023
Rechner LA, Maraldo MV, Smith EA, Lundgaard AY, Hjalgrim LL, MacKay RI, Aitkenhead AH, Aznar MC.   +7 more
europepmc   +1 more source

WE-H-BRA-07: Mechanistic Modelling of the Relative Biological Effectiveness of Heavy Charged Particles [PDF]

, 2016
McMahon, S, McNamara, A, Paganetti, H, Prise, K, Schuemann, J   +4 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Quantifying DNA strand breaks from targeted alpha emitters 225Ac and 227Th via Geant4-DNA: implications for RBE and cell survival

EJNMMI Physics
Background Targeted alpha therapy (TAT) utilizing high-LET alpha particles from radionuclides like 225Ac and 227Th shows promise in cancer treatment due to their ability to induce dense, localized DNA damage.
Samaneh Zolghadri, Payman Rafiepour, Hassan Yousefnia   +2 more
doaj   +1 more source

A systematic analysis of the particle irradiation data ensemble in the key of the microdosimetric kinetic model: Should clonogenic data be used for clinical relative biological effectiveness? [PDF]

Radiother Oncol, 2023
Suárez-García D, Cortés-Giraldo MA, Bertolet A.   +2 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Relative Biological Effectiveness of Neutrons for Prophage Induction [PDF]

International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1973
S, Hussain, L, Ehrenberg, G, Ahnström, M, Holmberg   +3 more
openaire   +2 more sources

Relative biological effectiveness in proton beam therapy – Current knowledge and future challenges

Clinical and Translational Radiation Oncology, 2018
Armin Lühr, Cläre von Neubeck, Mechthild Krause, Esther G.C. Troost   +3 more
doaj   +1 more source

Validation of the relative biological effectiveness of active-energy scanning carbon-ion radiotherapy on a commercial treatment planning system with a microdosimetic kinetic model. [PDF]

Radiat Oncol, 2023
Wang W, Sun W, Shen H, Zhao J.
europepmc   +1 more source