Results 121 to 130 of about 8,300,360 (253)

Quantifying DNA strand breaks from targeted alpha emitters 225Ac and 227Th via Geant4-DNA: implications for RBE and cell survival

EJNMMI Physics
Background Targeted alpha therapy (TAT) utilizing high-LET alpha particles from radionuclides like 225Ac and 227Th shows promise in cancer treatment due to their ability to induce dense, localized DNA damage.
Samaneh Zolghadri, Payman Rafiepour, Hassan Yousefnia   +2 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1989

, 1990
Annual report of the Marine Biological Laboratory in Woods Hole. 1989.
Marine Biological Laboratory (Woods Hole MA)
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Experimentally determined relative biological effectiveness of cyclotron-based epithermal neutrons designed for clinical BNCT: in vitro study. [PDF]

J Radiat Res, 2023
Hu N, Suzuki M, Masunaga SI, Kashino G, Kinashi Y, Chen YW, Liu Y, Uehara K, Mitsumoto T, Tanaka H, Ono K.   +10 more
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1980

, 1981
Annual report of the Marine Biological Laboratory in Woods Hole. 1980.
Marine Biological Laboratory (Woods Hole MA)
core  

Annual Report - Marine Biological Laboratory, 1933 [PDF]

, 1933
Annual report of the Marine Biological Laboratory in Woods Hole. 1933.
Marine Biological Laboratory (Woods Hole MA)
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1985

, 1986
Annual report of the Marine Biological Laboratory in Woods Hole. 1985.
Marine Biological Laboratory (Woods Hole MA)
core  

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Relative Biological Effectiveness Values of Spot-scanning Proton Beam Therapy at Shonan Kamakura General Hospital. [PDF]

In Vivo, 2023
Shiba S, Yamanaka M, Matsumoto K, Yamano A, Shimo T, Suzuki S, Yagihashi T, Nitta K, Ohno T, Tokuuye K, Omura M.   +10 more
europepmc   +1 more source