Results 101 to 110 of about 8,300,360 (253)

Annual Report - Marine Biological Laboratory, 1893

open access: yes, 1894
Annual report of the Marine Biological Laboratory in Woods Hole. 1893.
Marine Biological Laboratory (Woods Hole MA)
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

The Effect of Cell Oxygen Concentration on the Relative Biological Effectiveness of Low Energy X-rays [PDF]

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان
Background and Aim: Cancer treatment using ionizing radiation is an effective modality for the management and control of various cancers. The presence of oxygen inside the cell causes various damages to the DNA molecule.
Reza Shamsabadi, Hamid Reza Baghani
doaj  

Annual Report - Marine Biological Laboratory, 1950

open access: yes, 1951
Annual report of the Marine Biological Laboratory in Woods Hole. 1950.
Marine Biological Laboratory (Woods Hole MA)
core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Impact of hypoxic versus oxic conditions on local tumor control after proton irradiation in a rat prostate carcinoma

open access: yesClinical and Translational Radiation Oncology
Background and purpose: Hypoxia in tumors significantly contributes to radiation resistance, often leading to poor treatment outcomes. In vitro studies demonstrated that proton irradiation not only exhibits an increased relative biological effectiveness (
Michaela Schmitt   +5 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1941

open access: yes, 1942
Annual report of the Marine Biological Laboratory in Woods Hole. 1941.
Marine Biological Laboratory (Woods Hole MA)
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 2002

open access: yes, 2003
Annual report of the Marine Biological Laboratory in Woods Hole. 2002.
Marine Biological Laboratory (Woods Hole MA)
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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