Results 111 to 120 of about 8,300,360 (253)
Background: The assessment of RBE quantity in the treatment of cancer tumors with proton beams in treatment planning systems (TPS) is of high significance.
Hosseini M. A. +2 more
doaj
Annual Report - Marine Biological Laboratory, 1988
Annual report of the Marine Biological Laboratory in Woods Hole. 1988.
Marine Biological Laboratory (Woods Hole MA)
core
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1935
Annual report of the Marine Biological Laboratory in Woods Hole. 1935.
Marine Biological Laboratory (Woods Hole MA)
core
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1943
Annual report of the Marine Biological Laboratory in Woods Hole. 1943.
Marine Biological Laboratory (Woods Hole MA)
core
Proton therapy is a cutting-edge cancer treatment that delivers targeted radiation to tumors with little dose to surrounding healthy tissues. Multi-criteria optimization (MCO) can be employed to balance target coverage with healthy tissue sparing ...
Schubert, Mara
core +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1929
Annual report of the Marine Biological Laboratory in Woods Hole. 1929.
Marine Biological Laboratory (Woods Hole MA)
core
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source

