Results 41 to 50 of about 53,784 (251)

Ferulic Acid Attenuates Hypoxia/Reoxygenation Injury by Suppressing Mitophagy Through the PINK1/Parkin Signaling Pathway in H9c2 Cells

open access: yesFrontiers in Pharmacology, 2020
Ferulic acid protects against cardiac injury by scavenging free radicals. However, the role of mitophagy in ferulic acid-induced cardioprotection remains obscure.
Chenxi Luo   +5 more
semanticscholar   +1 more source

Nrf2-regulated redox signaling in brain endothelial cells adapted to physiological oxygen levels: Consequences for sulforaphane mediated protection against hypoxia-reoxygenation

open access: yesRedox Biology, 2020
Ischemic stroke is associated with a surge in reactive oxygen species generation during reperfusion. The narrow therapeutic window for the delivery of intravenous thrombolysis and endovascular thrombectomy limits therapeutic options for patients.
Gabriela Warpsinski   +6 more
semanticscholar   +1 more source

Nucleoredoxin Plays a Key Role in the Maintenance of Retinal Pigmented Epithelium Differentiation

open access: yesAntioxidants, 2022
Nucleoredoxin (Nrx) belongs to the Thioredoxin protein family and functions in redox-mediated signal transduction. It contains the dithiol active site motif Cys-Pro-Pro-Cys and interacts and regulates different proteins in distinct cellular pathways. Nrx
Mariana I. Holubiec   +7 more
doaj   +1 more source

Tumor reoxygenation for enhanced combination of radiation therapy and microwave thermal therapy using oxygen generation in situ by CuO nanosuperparticles under microwave irradiation

open access: yesTheranostics, 2020
As known, radiation therapy (RT) can exacerbate the degree of hypoxia of tumor cells, which induces serious resistance to RT and in turn, is the greatest obstacle to RT. Reoxygenation can restore the hypoxic state of tumor cells, which plays an important
Zeng-Zhen Chen   +10 more
semanticscholar   +1 more source

Delayed cardioplegic reoxygenation reduces reoxygenation injury in cyanotic immature hearts

open access: yesThe Annals of Thoracic Surgery, 1998
Hypoxemic developing hearts are susceptible to oxygen-mediated damage that occurs after reintroduction of molecular oxygen. This unintended hypoxemic/reoxygenation injury leads to lipid peroxidation and membrane damage and may contribute to postoperative cardiac dysfunction.
K, Ihnken, K, Morita, G D, Buckberg
openaire   +2 more sources

The therapeutic effect of controlled reoxygenation on chronic hypoxia-associated brain injury

open access: yesBiology Open, 2019
Cardiopulmonary bypass (CPB) is the most general technique applied in congenital heart disease (CHD). However, standard CPB poses a specific pathologic condition for patients during surgery: exposure to reoxygenation.
Zhenzhen Tu   +5 more
doaj   +1 more source

Roles for Plant Mitochondrial Alternative Oxidase Under Normoxia, Hypoxia, and Reoxygenation Conditions

open access: yesFrontiers in Plant Science, 2020
Alternative oxidase (AOX) is a non-energy conserving terminal oxidase in the plant mitochondrial electron transport chain (ETC) that has a lower affinity for oxygen than does cytochrome (cyt) oxidase.
Jayamini Jayawardhane   +6 more
doaj   +1 more source

The effects of dietary extract of mulberry leaf on growth performance, hypoxia-reoxygenation stress and biochemical parameters in various organs of fish

open access: yes, 2020
The study explored the effects of extract of mulberry leaves (EML) on the growth performance and hypoxia-reoxygenation stress as well as biochemical parameters in various organs of crucian carp (Carassius auratus gibelio).
Hua-Tao Li   +6 more
semanticscholar   +1 more source

The effect of erythropoietin on calcium levels during hypoxia reoxygenation injury in rats

open access: yesGeriatric Care, 2016
This experimental study examined the effect of erythropoietin (Epo) on rat model and particularly in a hypoxia-reoxygenation protocol. The effect of that molecule was studied biochemically using blood mean calcium levels (Ca++). Forty rats of mean weight
Constantinos Tsompos   +5 more
doaj   +1 more source

Metabolomic and Lipidomic Analysis of the Colorectal Adenocarcinoma Cell Line HT29 in Hypoxia and Reoxygenation

open access: yesMetabolites, 2023
The poor availability of oxygen and nutrients in malignant tumors drives the activation of various molecular responses and metabolic reprogramming in cancer cells. Hypoxic tumor regions often exhibit resistance to chemotherapy and radiotherapy.
Juan Carlos Alarcon Barrera   +3 more
doaj   +1 more source

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