Results 121 to 130 of about 15,574 (187)

VDR-RIPK1 Interaction and its Implications in Cell Death and Cancer Intervention

open access: yes, 2016
Receptor interacting protein kinase 1 (RIPK1) is an enzyme acting downstream of tumor necrosis factor alpha to control cell survival and death. RIPK1 expression has been reported to cause drug resistance in cancer cells; but so far, no published studies ...
Quarni, Waise
core  

Data: RIPK1 ablation in T cells results in spontaneous enteropathy and TNF-driven villus atrophy

open access: yes
: RIPK1 is a crucial regulator of cell survival, inflammation and cell death. Human RIPK1 deficiency leads to early-onset intestinal inflammation and peripheral T cell imbalance, though its role in \u3b1\u3b2T cell mediated intestinal homeostasis remains
Huysentruyt, Jelle   +13 more
core  

Lytic cell death in chronic lung diseases. [PDF]

open access: yesAm J Respir Cell Mol Biol
Siokas I   +3 more
europepmc   +1 more source

Enhancing Treg persistence by inhibiting necroptosis restrains autoimmune pathology. [PDF]

open access: yesJ Clin Invest
Wu Q   +11 more
europepmc   +1 more source

Harnessing necroptosis via RIPK1 degradation to potentiate radio-immunotherapy in cervical cancer. [PDF]

open access: yesBioact Mater
Wu T   +9 more
europepmc   +1 more source

RIPK1 protects naive and regulatory T cells from TNFR1-induced apoptosis

open access: yes
The T cell population size is stringently controlled before, during, and after immune responses, as improper cell death regulation can result in autoimmunity and immunodeficiency.
Vadi, MikeWE140002004877818020035469032f22bf32-01d6-11eb-bcbd-baa5996c31d1   +13 more
core  

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