Results 141 to 149 of about 12,004 (149)

Targeting RIPK1 for the treatment of human diseases

Proceedings of the National Academy of Sciences of the United States of America, 2019
Alexei Degterev, Dimitry Ofengeim, Junying Yuan   +2 more
exaly  

Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling

Trends in Cell Biology, 2016
Nieves Peltzer, Maurice Darding, Henning Walczak   +2 more
exaly  

RIPK1 mediates a disease-associated microglial response in Alzheimer’s disease

Proceedings of the National Academy of Sciences of the United States of America, 2017
Sonia Mazzitelli, Lauren Mifflin, Chengyu Zou   +2 more
exaly  

Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis

Proceedings of the National Academy of Sciences of the United States of America, 2018
Palak Amin, Ayaz Najafov, Heling Pan
exaly  

A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

Immunity
Gareth Muirhead, Rebecca Wilson
exaly  

RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation

Cell Metabolism
Bing Shan, Daichao Xu
exaly  

The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation

Immunity
Manolis Pasparakis, Chun Kim, Konstantinos Kelepouras   +2 more
exaly  

Palmitoylation licenses RIPK1 kinase activity and cytotoxicity in the TNF pathway

Molecular Cell
Bing Shan, Daichao Xu
exaly  

PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis

Molecular Cell
Xiaoyan Jiang, Bing Shan, Junying Yuan   +2 more
exaly