Results 131 to 140 of about 18,314 (233)

Eupatolide, isolated from Liriodendron tulipifera, sensitizes TNF-mediated dual modes of apoptosis and necroptosis by disrupting RIPK1 ubiquitination

Heliyon
Ubiquitination of RIPK1 plays an essential role in the recruitment of the IKK complex, an upstream component of pro-survival NF-κB. It also limits TNF-induced programmed cell death by inhibiting the spatial transition from TNFR1-associated complex-I to ...
Kyeong Ah Park, Chan Seok Jung, Kyung-Cheol Sohn, Eunjin Ju, Sanghee Shin, InWha Park, MinKyun Na, Gang Min Hur   +7 more
doaj   +1 more source

Influence of transplantation of neural stem cells on the expression of genes involved in the programmed cell death following ischemic brain stroke [PDF]

, 2019
Ishemijski moždani udar, te posljedične tkivna hipoksija i ishemija, uzrokuju značajno oštećenje moždanog tkiva. Jedan od pristupa u potrazi za pronalaskom uspješne obnove oštećenog tkiva uključuje primjenu matičnih stanica.
Hribljan, Valentina
core   +1 more source

SPATA2 promotes CYLD activity and regulates TNF‐induced NF‐κB signaling and cell death [PDF]

, 2016
K63‐ and Met1‐linked ubiquitylation are crucial posttranslational modifications for TNF receptor signaling. These non‐degradative ubiquitylations are counteracted by deubiquitinases (DUBs), such as the enzyme CYLD, resulting in an appropriate signal ...
Borner, Christoph, Brauns‐Schubert, Prisca, Dengjel, Jörn, Dumit, Veronica, Jakob, Celia, Maurer, Ulrich, Preiss, Florian, Schlicher, Lisa, Wissler, Manuela   +8 more
core   +1 more source

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]

, 2020
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima, Al-Herz, Waleed, Bousfiha, Aziz, Casanova, Jean-Laurent, Chatila, Talal, Cunningham-Rundles, Charlotte, Etzioni, Amos, Franco, Jose Luis, Holland, Steven M, Jeddane, Leila, Klein, Christoph, Morio, Tomohiro, Ochs, Hans D, Oksenhendler, Eric, Picard, Capucine, Puck, Jennifer, Sullivan, Kathleen E, Tangye, Stuart G, Torgerson, Troy R   +18 more
core  

Necroptosis of Glycolytic Dendritic Cells Enhances Activation of Gamma Delta T Cells [PDF]

, 2016
Gamma delta (gd) T lymphocytes are a poorly understood class of immune cells that accumulate at sites of inflammation due to infection or autoimmunity. Part of the mystery of this T cell subset derives from lack of knowledge of ligands that bind to the T
Bashant, Kathleen R
core   +1 more source

RIPK1 Inhibitor GSK3145095 [PDF]

, 2020
openaire   +1 more source

RIPK1 wt Allele [PDF]

, 2020
openaire   +1 more source

Primary immunodeficiency reveals importance of RIPK1 [PDF]

Nature Reviews Rheumatology, 2018
openaire   +2 more sources

Cell Death Response to DNA Damage. [PDF]

, 2019
The cell death response to DNA damage is discussed in this Perspectives piece with cancer as the backdrop because DNA damaging agents (DDA) are widely used to treat cancer.
Wang, Jean YJ
core   +1 more source

Development of a New Positron Emission Tomography Imaging Radioligand Targeting RIPK1 in the Brain and Characterization in Alzheimer's Disease

Advanced Science
Targeting receptor‐interacting protein kinase 1 (RIPK1) has emerged as a promising therapeutic stratagem for neurodegenerative disorders, particularly Alzheimer's disease (AD).
Ping Bai, Yu Lan, Yan Liu, Prasenjit Mondal, Ashley Gomm, Yulong Xu, Yanli Wang, Yongle Wang, Leyi Kang, Lili Pan, Frederick A. Bagdasarian, Madelyn Hallisey, Fleur Lobo, Breanna Varela, Se Hoon Choi, Stephen N. Gomperts, Hsiao‐Ying Wey, Shiqian Shen, Rudolph E. Tanzi, Changning Wang, Can Zhang   +20 more
doaj   +1 more source