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Advances in research on RNA methylation and cancer radiotherapy resistance [PDF]
Frontiers in OncologyRNA methylation is a type of reversible chemical modification in epitranscriptomics that influences gene expression by dynamically regulating RNA functions.
Hui Liu +5 more
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Regulation of RNA methylation linked to drug resistance in gastric cancer [PDF]
Frontiers in Cell and Developmental BiologyIn global terms, gastric cancer (GC) represents one of the most commonly occurring malignancies. It is positioned as the fifth most frequent cancer in terms of incidence and stands as the third primary contributor to cancer-related mortality.
Zihan Yang +5 more
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PathoRM: Computational inference of pathogenic RNA methylation sites by incorporating multi-view features. [PDF]
PLoS Computational BiologyIdentifying pathogenic RNA methylation sites with a reasonable biological explanation has important implications for the treatment of diseases. Due to the limitations of in vitro experiments in identifying pathogenic RNA methylation sites, there is a ...
Hui Liu, Jiani Ma, Xianjun Ma, Lin Zhang
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Single-cell analysis reveal cell-type-specific RNA methylation patterns in breast cancer [PDF]
Journal of International Medical ResearchObjective This study aimed to investigate cell-type-specific RNA methylation patterns in primary breast cancers and metastatic lymph nodes and explore their roles in cancer progression and immune regulation.
Shengtao Huang +6 more
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Integration of multi-omics data reveals dysregulated RNA methylation in retinal pigment epithelium drives age-related macular degeneration [PDF]
International Journal of OphthalmologyAIM: To investigate the role of RNA methylation in retinal pigment epithelial (RPE) cells in age-related macular degeneration (AMD). METHODS: RNA methylation-related gene expression profiles of AMD patient and normal control retinal pigment epithelium ...
Ya-Jun Gong +4 more
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RNA methylation in plants: An overview
Frontiers in Plant Science, 2023 RNA methylation is an important post-transcriptional modification that influences gene regulation. Over 200 different types of RNA modifications have been identified in plants.
Harshraj Shinde +4 more
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Roles of RNA Methylation on Tumor Immunity and Clinical Implications
Frontiers in Immunology, 2021 RNA methylation is a kind of RNA modification that exists widely in eukaryotes and prokaryotes. RNA methylation occurs not only in mRNA but also in ncRNA.
Maorun Zhang +5 more
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IET Systems Biology, 2022 N6‐methyladenosine (m6A) RNA methylation is correlated with carcinogenesis and dynamically possessed through the m6A RNA methylation regulators. This paper aimed to explore 13 m6A RNA methylation regulators' role in gastrointestinal cancer (GIC) and ...
Yandong Miao +6 more
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Effects of RNA methylation on Tumor angiogenesis and cancer progression
Molecular Cancer, 2023 Tumor angiogenesis plays vital roles in the growth and metastasis of cancer. RNA methylation is one of the most common modifications and is widely observed in eukaryotes and prokaryotes. Accumulating studies have revealed that RNA methylation affects the
Mingyu Han +6 more
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Computational and Structural Biotechnology Journal, 2023 As an internal modification of transcripts, RNA methylation determines RNA fate by changing RNA–protein binding affinity. In plants, RNA methylation is ubiquitous and is involved in all aspects of RNA post-transcriptional regulation.
Xiaojun Li +13 more
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