Results 11 to 20 of about 503,240 (288)
RNA modifications in brain tumorigenesis [PDF]
Acta Neuropathologica Communications, 2020 RNA modifications are emerging as critical regulators in cancer biology, thanks to their ability to influence gene expression and the predominant protein isoforms expressed during cell proliferation, migration, and other pro-oncogenic properties.
Albert Z. Huang +2 more
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Instrumental analysis of RNA modifications [PDF]
Critical Reviews in Biochemistry and Molecular Biology, 2021 Organisms from all domains of life invest a substantial amount of energy for the introduction of RNA modifications into nearly all transcripts studied to date. Instrumental analysis of RNA can focus on the modified residues and reveal the function of these epitranscriptomic marks.
Yasemin Yoluç +9 more
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Frontiers in Insect ScienceMore than 100 RNA chemical modifications to cellular RNA have been identified. N6-methyladenosine (m6A) is the most prevalent modification of mRNA. RNA modifications have recently attracted significant attention due to their critical role in regulating ...
Yaoyu Jiao +2 more
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Understanding RNA modifications: the promises and technological bottlenecks of the ‘epitranscriptome’ [PDF]
Open Biology, 2017 The discovery of mechanisms that alter genetic information via RNA editing or introducing covalent RNA modifications points towards a complexity in gene expression that challenges long-standing concepts.
Matthias Schaefer +2 more
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RNA Modifications and Epitranscriptomics
Genomics, Proteomics & Bioinformatics, 2023 Chengqi Yi, Jianhua Yang
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Non‐m6A RNA modifications in haematological malignancies [PDF]
Clinical and Translational MedicineDysregulated RNA modifications, stemming from the aberrant expression and/or malfunction of RNA modification regulators operating through various pathways, play pivotal roles in driving the progression of haematological malignancies.
Meiling Chen +4 more
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RNA modifications in pulmonary diseases
MedCommThreatening public health, pulmonary disease (PD) encompasses diverse lung injuries like chronic obstructive PD, pulmonary fibrosis, asthma, pulmonary infections due to pathogen invasion, and fatal lung cancer.
Weiwei Qian +5 more
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RNA modifications detection by comparative Nanopore direct RNA sequencing [PDF]
Nature Communications, 2021 Nanopore direct RNA Sequencing data contain information about the presence of RNA modifications, but their detection poses substantial challenges. Here the authors introduce Nanocompore, a new methodology for modification detection from Nanopore data.
Adrien Leger +18 more
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Small RNA modifications in Alzheimer's disease [PDF]
Neurobiology of Disease, 2020 BackgroundWhile significant advances have been made in uncovering the aetiology of Alzheimer's disease and related dementias at the genetic level, molecular events at the epigenetic level remain largely undefined.
Xudong Zhang +7 more
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Cancer Management and Research, 2022 Zhiyuan Yang,1,2,* Siyu Zhang,1,2,* Tian Xia,1,2,* Yue Fan,1,2 Ying Shan,1,2 Kaiwen Zhang,1,2 Jiayan Xiong,1,2 Miao Gu,1,2 Bo You1,2 1Department of Otolaryngology Head and Neck Surgery, Affiliated Hospital of Nantong University, Medical ...
Yang Z +8 more
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