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Frontiers in Insect ScienceMore than 100 RNA chemical modifications to cellular RNA have been identified. N6-methyladenosine (m6A) is the most prevalent modification of mRNA. RNA modifications have recently attracted significant attention due to their critical role in regulating ...
Yaoyu Jiao +2 more
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RNA Modifications and Epitranscriptomics
Genomics, Proteomics & Bioinformatics, 2023 Chengqi Yi, Jianhua Yang
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RNA modifications in pulmonary diseases
MedCommThreatening public health, pulmonary disease (PD) encompasses diverse lung injuries like chronic obstructive PD, pulmonary fibrosis, asthma, pulmonary infections due to pathogen invasion, and fatal lung cancer.
Weiwei Qian +5 more
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RNA modifications go viral. [PDF]
PLoS Pathogens, 2017 Nandan S Gokhale, Stacy M Horner
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RNA modifications and cancer [PDF]
RNA Biology, 2020 RNA plays essential roles in not only translating nucleic acids into proteins, but also in gene regulation, environmental interactions and many human diseases. Nature uses over 150 chemical modifications to decorate RNA and diversify its functions. With the fast-growing RNA research in the burgeoning field of 'epitranscriptome', a term describes post ...
Phensinee Haruehanroengra +4 more
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RNA modification mapping with JACUSA2 [PDF]
Genome Biology, 2022 Abstract Several high-throughput antibody-free methods for RNA modification detection from sequencing data have been developed. We present JACUSA2 as a versatile software solution and comprehensive analysis framework for RNA modification detection assays that are based on either the Illumina or Nanopore platform ...
Michael Piechotta +4 more
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Novel Modifications in RNA [PDF]
ACS Chemical Biology, 2011 The past several years have seen numerous reports of new chemical modifications for use in RNA. In addition, in that time period, we have seen the discovery of several previously unknown naturally occurring modifications that impart novel properties on the parent RNAs.
Kelly, Phelps +2 more
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The RNA modification database [PDF]
Nucleic Acids Research, 1996 The RNA modification database provides a comprehensive listing of posttranscriptionally modified nucleosides from all RNAs, and is maintained as an updated version of the initial printed report [Limbach,P.A., Crain,P.F. and McCloskey,J.A. (1994)Nucleic Acids Res. , 22, 2183-2196].
Pamela F. Crain, James A. McCloskey
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Detection of RNA modifications [PDF]
RNA Biology, 2010 RNA nucleotide modifications are typically of low abundance and frequently go unnoticed by standard detection methods of molecular biology and cell biology. With a burst of knowledge intruding from such diverse areas as genomics, structural biology, regulation of gene expression and immunology, it becomes increasingly clear that many exciting functions
Stefanie, Kellner +2 more
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ALKBHs-facilitated RNA modifications and de-modifications [PDF]
DNA Repair, 2016 The AlkB gene that protects E.coli against methylation damage to DNA was identified more than 3 decades ago. 20 years later, the AlkB protein was shown to catalyze repair of methylated DNA base lesions by oxidative demethylation. Two human AlkB homologs were characterized with similar DNA repair activities and seven additional human AlkB homologs were ...
Endalkachew, A Alemu +2 more
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