Results 41 to 50 of about 503,240 (288)

A New Epigenetic Crosstalk: Chemical Modification Information Flow

Advanced Genetics, 2023
Central dogma is the most fundamental hypothesis in the field of molecular biology and explains the genetic information flow from DNA to protein. Beyond residue‐by‐residue transmission of sequential information, chemical modifications of DNA, RNA, and ...
Hongwoo Lee, Young‐Joon Park, Pil Joon Seo   +2 more
doaj   +1 more source

Epitranscriptomics: RNA Modifications in Bacteria and Archaea [PDF]

, 2018
The increasingly complex functionality of RNA is contrasted by its simple chemical composition. RNA is generally built from only four different nucleotides (adenine, guanine, cytosine, and uracil).
Jäschke, A., Höfer, K.
core   +1 more source

Regulation and roles of RNA modifications in aging-related diseases [PDF]

, 2022
With the aging of the global population, accumulating interest is focused on manipulating the fundamental aging-related signaling pathways to delay the physiological aging process and eventually slow or prevent the appearance or severity of multiple ...
Helge Immo Lehmann, Li , G., Priyanka Gokulnath, Gokulnath, Priyanka, Su, D., Vulugundam, G., Gokulnath, P., Lingying Zhang, Song, Shannan, Jiapaer, Z., Gong, Y., Zhang, Lingying, Zhang, L., Gong, Ye, Li, Guoping, Zeyidan Jiapaer, Hua, Lingyang, Guoping Li, Shannan Song, Dingwen Su, Song, S., Jiapaer, Zeyidan, Lehmann, Helge Immo, Gururaja Vulugundam, Vulugundam, Gururaja, Lingyang Hua, Hua, L., Lehmann, H., Ye Gong, Su, Dingwen   +29 more
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Cellular Dynamics of RNA Modification [PDF]

Accounts of Chemical Research, 2011
Five decades of research have identified more than 100 ribonucleosides that are post-transcriptionally modified. Many modified nucleosides are conserved throughout bacteria, archaea, and eukaryotes, while some are unique to each branch of life. However, the cellular and functional dynamics of RNA modification remain largely unexplored, mostly because ...
Chengqi, Yi, Tao, Pan
openaire   +2 more sources

Research Progress for RNA Modifications in Physiological and Pathological Angiogenesis

Frontiers in Genetics, 2022
As a critical layer of epigenetics, RNA modifications demonstrate various molecular functions and participate in numerous biological processes. RNA modifications have been shown to be essential for embryogenesis and stem cell fate.
Hui-Ming Chen, Hui-Ming Chen, Hang Li, Meng-Xian Lin, Wei-Jie Fan, Yi Zhang, Yan-Ting Lin, Yan-Ting Lin, Shu-Xiang Wu, Shu-Xiang Wu   +9 more
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The impact of RNA modifications on the biology of DNA virus infection

European Journal of Cell Biology, 2022
Approximately 170 RNA modifications have been identified and these are critical for determining the fate and function of cellular RNAs. Similar to human transcripts, viral RNAs possess an extensive RNA modification landscape.
Suba Rajendren, John Karijolich
doaj   +1 more source

Chemical Modifications of Ribosomal RNA

, 2022
AbstractCellular RNAs in all three kingdoms of life are modified with diverse chemical modifications. These chemical modifications expand the topological repertoire of RNAs, and fine-tune their functions. Ribosomal RNA in yeast contains more than 100 chemically modified residues in the functionally crucial and evolutionary conserved regions.
Sunny, Sharma, Karl-Dieter, Entian
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RNA modifications in cardiovascular health and disease [PDF]

, 2023
RNA is not always a faithful copy of DNA. Advances in tools enabling the interrogation of the exact RNA sequence have permitted revision of how genetic information is transferred.
Gatsiou, Aikaterini, Stellos, Konstantinos   +1 more
core  

The role of RNA modification in hepatocellular carcinoma

Frontiers in Pharmacology, 2022
Hepatocellular carcinoma (HCC) is a highly mortal type of primary liver cancer. Abnormal epigenetic modifications are present in HCC, and RNA modification is dynamic and reversible and is a key post-transcriptional regulator.
Qiang Feng, Dongxu Wang, Tianyi Xue, Chao Lin, Yongjian Gao, Liqun Sun, Ye Jin, Dianfeng Liu   +7 more
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Effects of Epitranscriptomic RNA Modifications on the Catalytic Activity of SARS-CoV-2 Replication Complex [PDF]

, 2023
Like other viruses, SARS-CoV-2 causes different symptoms and different degrees of harmfulness to different individuals. Potential reasons include an individual’s viral dose exposure, the affinity of an individual’s ACE2 to the spike protein of the virus,
Emma , Burke, Reed , Arneson, Yinan, Yuan, Adikari M. D. N. , Eriyagama, Alexander , Apostle, Komal , Chillar, Yipeng, Yin, Shiyue, Fang   +7 more
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