Results 21 to 30 of about 798,047 (345)
Regulatory role of RNA N6-methyladenosine modifications during skeletal muscle development
Frontiers in Cell and Developmental Biology, 2022 Functional cells in embryonic myogenesis and postnatal muscle development undergo multiple stages of proliferation and differentiation, which are strict procedural regulation processes.
Baojun Yu +6 more
doaj +1 more source
The Splice of Life: Does RNA Processing Have a Role in HIV-1 Persistence?
Viruses, 2021 Antiretroviral therapy (ART) suppresses HIV-1 replication but does not eradicate the virus. Persistence of HIV-1 latent reservoirs in ART-treated individuals is considered the main obstacle to achieving an HIV-1 cure.
Alexander O. Pasternak, Ben Berkhout
doaj +1 more source
Alternative Polyadenylation: a new frontier in post transcriptional regulation
Biomarker Research, 2020 Polyadenylation of pre-messenger RNA (pre-mRNA) specific sites and termination of their downstream transcriptions are signaled by unique sequence motif structures such as AAUAAA and its auxiliary elements.
F. Ren +4 more
semanticscholar +1 more source
R-loops at microRNA encoding loci promote co-transcriptional processing of pri-miRNAs in plants
Nature Plants, 2022 In most organisms, the maturation of nascent RNAs is coupled to transcription. Unlike in animals, the RNA polymerase II (RNAPII) transcribes microRNA genes (MIRNAs) as long and structurally variable pri-miRNAs in plants.
Lucía Gonzalo +11 more
semanticscholar +1 more source
RNA-binding proteins in tumor progression
Journal of Hematology & Oncology, 2020 RNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and important biological functions. They are critical to maintain the transcriptome through post-transcriptionally controlling the processing and transportation of RNA ...
Hai Qin +6 more
doaj +1 more source
HibeRNAtion: HIV-1 RNA Metabolism and Viral Latency
Frontiers in Cellular and Infection Microbiology, 2022 HIV-1 infection remains non-curative due to the latent reservoir, primarily a small pool of resting memory CD4+ T cells bearing replication-competent provirus.
Raquel Crespo +4 more
doaj +1 more source
Bio-Protocol, 2021 Cytidine-to-uridine (C-to-U) RNA editing is one of the most important post-transcriptional RNA processing in plant mitochondria and chloroplasts. Several techniques have been developed to detect the RNA editing efficiency in plant mitochondria and ...
Yang Yang, Weixing Shan
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Dynamics of transcriptional and post-transcriptional regulation
Briefings Bioinform., 2020 Despite gene expression programs being notoriously complex, RNA abundance is usually assumed as a proxy for transcriptional activity. Recently developed approaches, able to disentangle transcriptional and post-transcriptional regulatory processes, have ...
Mattia Furlan +2 more
semanticscholar +1 more source
RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]
, 2016 Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan +17 more
core +2 more sources
3’ Rapid Amplification of cDNA Ends (3’ RACE) Using Arabidopsis Samples
Bio-Protocol, 2015 Production of functional eukaryotic RNA is a very elaborate process that involves a complex interplay between transcription and various RNA processing activities, including splicing, 5’ capping, and 3’ cleavage and polyadenylation (Bentley, 2014 ...
Encarnación Rodríguez-Cazorla +6 more
doaj +1 more source