RNA Metabolism Guided by RNA Modifications: The Role of SMUG1 in rRNA Quality Control
Biomolecules, 2021 RNA modifications are essential for proper RNA processing, quality control, and maturation steps. In the last decade, some eukaryotic DNA repair enzymes have been shown to have an ability to recognize and process modified RNA substrates and thereby ...
Lisa Lirussi +5 more
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An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites
npj Aging and Mechanisms of Disease, 2017 Muscle degeneration: RNA structures as modulator of muscle function Transcriptional and post-transcriptional regulation of gene expression has a fundamental role in shaping the protein landscape.
Tooba Abbassi-Daloii +6 more
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The retrovirus RNA trafficking granule: from birth to maturity
Retrovirology, 2006 Post-transcriptional events in the life of an RNA including RNA processing, transport, translation and metabolism are characterized by the regulated assembly of multiple ribonucleoprotein (RNP) complexes.
Mouland Andrew J +2 more
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Transfer RNA Post-Transcriptional Processing, Turnover, and Subcellular Dynamics in the YeastSaccharomyces cerevisiae [PDF]
Genetics, 2013 AbstractTransfer RNAs (tRNAs) are essential for protein synthesis. In eukaryotes, tRNA biosynthesis employs a specialized RNA polymerase that generates initial transcripts that must be subsequently altered via a multitude of post-transcriptional steps before the tRNAs beome mature molecules that function in protein synthesis.
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Circadian rhythms and post-transcriptional regulation in higher plants
Frontiers in Plant Science, 2015 The circadian clock of plants allows them to cope with daily changes in their environment. This is accomplished by the rhythmic regulation of gene expression, in a process that involves many regulatory steps.
Andres eRomanowski +1 more
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Control of RNA degradation in cell fate decision
Frontiers in Cell and Developmental Biology, 2023 Cell fate is shaped by a unique gene expression program, which reflects the concerted action of multilayered precise regulation. Substantial research attention has been paid to the contribution of RNA biogenesis to cell fate decisions.
Mingqiang Deng +5 more
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Production of Viral mRNA in Adenovirus-Transformed Cells by the Post-Transcriptional Processing of Heterogeneous Nuclear RNA Containing Viral and Cell Sequences [PDF]
Journal of Virology, 1973 Adenovirus 2-transformed cells contain virus-specific sequences which are covalently linked to cell-specific RNA sequences in heterogeneous nuclear RNA (HnRNA) molecules larger than 45 S . Virus sequences are identified by hybridization to viral DNA, and the cell sequences are detected by hybridization to cellular ...
R, Wall, J, Weber, Z, Gage, J E, Darnell
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Developmental Biology, 2021 Mesenchymal stem cells are candidates for therapeutic strategies in periodontal repair due to their osteogenic potential. In this study, we identified epigenetic markers during osteogenic differentiation, taking advantage of the individual pattern of mesenchymal cells of the periodontal ligament with high (h-PDLCs) and low (l-PDLCs) osteogenic capacity.
Rahyza I.F. Assis +10 more
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HIV latency reversing agents act through Tat post translational modifications
Retrovirology, 2018 Background Different classes of latency reversing agents (LRAs) are being evaluated to measure their effects in reactivating HIV replication from latently infected cells.
Georges Khoury +9 more
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Identification of human mitochondrial RNA cleavage sites and candidate RNA processing factors
BMC Biology, 2022 Background The human mitochondrial genome is transcribed as long strands of RNA containing multiple genes, which require post-transcriptional cleavage and processing to release functional gene products that play vital roles in cellular energy production.
Guillermo Carbajosa +2 more
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