Results 31 to 40 of about 798,047 (345)
Genome Biology, 2021 Background Cellular RNA-binding proteins (RBPs) have multiple roles in post-transcriptional control, and some are shown to bind DNA. However, the global localization and the general chromatin-binding ability of RBPs are not well-characterized and remain ...
Yue Ren +16 more
doaj +1 more source
eLife, 2022 Protein arginine methyltransferases (PRMTs) are required for the regulation of RNA processing factors. Type I PRMT enzymes catalyze mono- and asymmetric dimethylation; Type II enzymes catalyze mono- and symmetric dimethylation. To understand the specific
Maxim I Maron +7 more
doaj +1 more source
Circular RT-PCR Assay Using Arabidopsis Samples
Bio-Protocol, 2015 Post-transcriptional processing is critical for RNA biogenesis, in which conventional functional RNA transcripts are generated, such as messenger RNAs (mRNAs), transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs) for translation as well as emerging non ...
Runlai Hang +4 more
doaj +1 more source
Journal of Developmental Biology, 2018 An outstanding question in developmental neurobiology is how RNA processing events contribute to the regulation of neurogenesis. RNA processing events are increasingly recognized as playing fundamental roles in regulating multiple developmental events ...
Eugenia C. Olesnicky, Ethan G. Wright
doaj +1 more source
Cotranscriptional kinetic folding of RNA secondary structures including pseudoknots [PDF]
Journal of Computational Biology, 2021, 2020 Computational prediction of RNA structures is an important problem in computational structural biology. Studies of RNA structure formation often assume that the process starts from a fully synthesized sequence. Experimental evidence, however, has shown that RNA folds concurrently with its elongation.
arxiv +1 more source
Altered RNA Processing in Cancer Pathogenesis and Therapy.
Cancer Discovery, 2019 Major advances in our understanding of cancer pathogenesis and therapy have come from efforts to catalog genomic alterations in cancer. A growing number of large-scale genomic studies have uncovered mutations that drive cancer by perturbing ...
Esther A. Obeng +2 more
semanticscholar +1 more source
Molecular Cancer, 2019 N6-methyladenosine (m6A) modification, the most abundant internal methylation of eukaryotic RNA transcripts, is critically implicated in RNA processing.
T. Lan +15 more
semanticscholar +1 more source
Complex RNA metabolism in the chloroplast: an update on the psbB operon [PDF]
, 2012 Expression of most plastid genes involves multiple post-transcriptional processing events, such as splicing, editing, and intercistronic processing. The latter involves the formation of mono-, di-, and multicistronic transcripts, which can further be ...
Jörg Meurer, Rhea Stoppel
core +1 more source
Probing the limits to microRNA-mediated control of gene expression [PDF]
, 2016 According to the `ceRNA hypothesis', microRNAs (miRNAs) may act as mediators of an effective positive interaction between long coding or non-coding RNA molecules, carrying significant potential implications for a variety of biological processes.
De Martino, Andrea +3 more
core +4 more sources
RNA Metabolism Guided by RNA Modifications: The Role of SMUG1 in rRNA Quality Control
Biomolecules, 2021 RNA modifications are essential for proper RNA processing, quality control, and maturation steps. In the last decade, some eukaryotic DNA repair enzymes have been shown to have an ability to recognize and process modified RNA substrates and thereby ...
Lisa Lirussi +5 more
doaj +1 more source