Results 61 to 70 of about 798,047 (345)

Cellulosome stoichiometry in Clostridium cellulolyticum is regulated by selective RNA processing and stabilization

Nature Communications, 2015
The mechanism, physiological relevance and evolutionary implication of selective RNA processing and stabilization (SRPS) remain elusive. Here we report the genome-wide maps of transcriptional start sites (TSs) and post-transcriptional processed sites ...
Cheng-xi Xu, Ranran Huang, Lin Teng, Xiaoyan Jing, Jianqiang Hu, G. Cui, Yilin Wang, Q. Cui, Jian Xu   +8 more
semanticscholar   +1 more source

DICER-LIKE2 plays a primary role in transitive silencing of transgenes in Arabidopsis. [PDF]

, 2008
Dicer-like (DCL) enzymes play a pivotal role in RNA silencing in plants, processing the long double-stranded RNA (dsRNA) that triggers silencing into the primary short interfering RNAs (siRNAs) that mediate it.
Bowman, Lewis H, Chen, Xuemei, Endres, Matthew W, Li, Junjie, Mlotshwa, Sizolwenkosi, Peragine, Angela, Poethig, R Scott, Pruss, Gail J, Vance, Vicki   +8 more
core   +5 more sources

Molecular Network Analysis Suggests a Logical Hypothesis for the Pathological Role of C9orf72 in Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

Journal of Central Nervous System Disease, 2014
Background Expanded GGGGCC hexanucleotide repeats, ranging from hundreds to thousands in number, located in the noncoding region of the chromosome 9 open reading frame 72 ( C9orf72 ) gene represent the most common genetic abnormality for familial and ...
Jun-Ichi Satoh, Yoji Yamamoto, Shouta Kitano, Mika Takitani, Naohiro Asahina, Yoshihiro Kino   +5 more
doaj   +1 more source

Post-Transcriptional Regulation by Poly(ADP-ribosyl)ation of the RNA-Binding Proteins

International Journal of Molecular Sciences, 2013
Gene expression is intricately regulated at the post-transcriptional level by RNA-binding proteins (RBPs) via their interactions with pre-messenger RNA (pre-mRNA) and mRNA during development.
Yingbiao Ji, A. Tulin
semanticscholar   +1 more source

RNA-based regulation: dynamics and response to perturbations of competing RNAs [PDF]

, 2013
The observation that, through a titration mechanism, microRNAs (miRNAs) can act as mediators of effective interactions among their common targets (competing endogenous RNAs or ceRNAs) has brought forward the idea ('ceRNA hypothesis') that RNAs can ...
De Martino, Andrea, Figliuzzi, Matteo, Marinari, Enzo   +2 more
core   +3 more sources

Polynucleotide phosphorylase: Not merely an RNase but a pivotal post-transcriptional regulator

PLoS Genetics, 2018
Almost 60 years ago, Severo Ochoa was awarded the Nobel Prize in Physiology or Medicine for his discovery of the enzymatic synthesis of RNA by polynucleotide phosphorylase (PNPase).
Todd A. Cameron, L. Matz, Nicholas R. De Lay   +2 more
semanticscholar   +1 more source

Synthetic RNA modules for fine-tuning gene expression levels in yeast by modulating RNase III activity [PDF]

, 2011
The design of synthetic gene networks requires an extensive genetic toolbox to control the activities and levels of protein components to achieve desired cellular functions.
Alper, Alper, Alper, Anderson, Andrew H. Babiskin, Babiskin, Babiskin, Basu, Beisel, Callura, Caponigro, Carrier, Chanfreau, Chanfreau, Chao, Christina D. Smolke, Danin-Kreiselman, Elela, Ellis, Elowitz, Gardner, Ge, Gietz, Hawkins, Hawkins, Isaacs, Jensen, Jin, Jones, Keiler, Lamontagne, Lamontagne, Lamontagne, Lamontagne, Lamontagne, Lamontagne, Larose, Lautz, Lavoie, Lee, Louis, Lutz, Mateus, Misra, Nevoigt, Ng, Nguyen, Ostergaard, Paradise, Pfleger, Ro, Salis, Sambrook, Szczebara, Vasudevan, Veen, Win, Wu, Wu, Zhou, Zhou, Zhu, Zhu   +62 more
core   +3 more sources

Transcriptional and post-transcriptional processes regulate expression of RNA encoding the small subunit of ribulose-1, 5-biphosphate carboxylase differently in petunia and in soybean [PDF]

Nucleic Acids Research, 1990
The effects of white light, far-red light and darkness on the in vitro transcription and RNA levels of the small subunit of ribulose-1,5-bisphosphate carboxylase (rbcS) were investigated in petunia and in soybean. In petunia plants treated with 48 hours of darkness the in vitro transcription rate of two of the rbcS subfamilies of petunia, rbcS A and ...
Deborah M. Thompson, Richard B. Meagher
openaire   +3 more sources

Analysis of Transcriptome and Epitranscriptome in Plants Using PacBio Iso-Seq and Nanopore-Based Direct RNA Sequencing

Frontiers in Genetics, 2019
Nanopore sequencing from Oxford Nanopore Technologies (ONT) and Pacific BioSciences (PacBio) single-molecule real-time (SMRT) long-read isoform sequencing (Iso-Seq) are revolutionizing the way transcriptomes are analyzed.
Liangzhen Zhao, Hangxiao Zhang, Markus V. Kohnen, Kasavajhala V. S. K. Prasad, Lianfeng Gu, Anireddy S. N. Reddy   +5 more
doaj   +1 more source

A Genome-Scale Atlas Reveals Complex Interplay of Transcription and Translation in an Archaeon

mSystems, 2023
The scale of post-transcriptional regulation and the implications of its interplay with other forms of regulation in environmental acclimation are underexplored for organisms of the domain Archaea.
Alan P. R. Lorenzetti, Ulrike Kusebauch, Lívia S. Zaramela, Wei-Ju Wu, João P. P. de Almeida, Serdar Turkarslan, Adrián L. G. de Lomana, José V. Gomes-Filho, Ricardo Z. N. Vêncio, Robert L. Moritz, Tie Koide, Nitin S. Baliga   +11 more
doaj   +1 more source