Results 1 to 10 of about 22,858 (247)
Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein [PDF]
Scavenger receptor class B type I (SR-BI) has been established as the primary mediator of the selective transfer of lipids from HDL to mammalian cells.
Kristin Gillotte-Taylor +4 more
doaj +3 more sources
Loss of Function of Scavenger Receptor SCAV-5 Protects C. elegans Against Pathogenic Bacteria
Scavenger receptors play a critical role in innate immunity by acting as the pattern-recognition receptors. There are six class B scavenger receptors homologs in C. elegans.
Aixiao Luo +5 more
doaj +1 more source
A gut feeling for drugs that have metabolic benefits
Resveratrol (REV) is a natural polyphenol with anti-obesity effects. However, the mechanisms remain unclear due to its low bioavailability and the lack of defined membrane-bound or nuclear receptors.
Eryun Zhang, Alon Agua, Wendong Huang
doaj +1 more source
There is a tight relationship between fertility and changes in cholesterol metabolism during spermatogenesis. In the testis, class B scavenger receptors (SR-B) SR-BI, SR-BII, and LIMP II mediate the selective uptake of cholesterol esters from HDL, which ...
María Emilia Casado +8 more
doaj +1 more source
Modified forms of LDL, including oxidized low density lipoprotein (OxLDL), contribute to macrophage lipid accumulation in the vessel wall. Despite the pathophysiological importance of uptake pathways for OxLDL, the molecular details of OxLDL endocytosis ...
Bing Sun +5 more
doaj +1 more source
Overflow phenomenon in serum lutein after supplementation: a systematic review supported with SNPs analyses [PDF]
Lutein, a type of carotenoids, is found to delay the onset and progression of age-related macular degeneration (AMD). Several lutein supplementation studies showed that after an initial increase, lutein serum levels demonstrated a subsequent decrease ...
Abdulrahman M Alharbi +2 more
doaj +1 more source
ApoA-II modulates the association of HDL with class B scavenger receptors SR-BI and CD36
The class B scavenger receptors SR-BI and CD36 exhibit a broad ligand binding specificity. SR-BI is well characterized as a HDL receptor that mediates selective cholesteryl ester uptake from HDL.
Maria C. de Beer +5 more
doaj +1 more source
The absence of MHC class II antigen presentation and multiple pathogen recognition receptors in the Atlantic cod has not impaired its immune response however how underlying mechanisms have adapted remains largely unknown.
Xingkun Jin +9 more
doaj +1 more source
Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro-inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be induced by its predominant cell wall glycolipid, trehalose 6,6 ...
Dawn M E Bowdish +8 more
doaj +1 more source
Contribution of Glycation and Oxidative Stress to Thyroid Gland Pathology—A Pilot Study
The patho-mechanism of changes in the thyroid gland, including carcinogenesis, is a complex process, which involves oxidative stress. The goal of our investigation was to verify the extent of stress in the thyroid gland related to glycation.
Aleksandra Kuzan +8 more
doaj +1 more source

