Results 1 to 10 of about 22,858 (247)

Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein [PDF]

open access: yesJournal of Lipid Research, 2001
Scavenger receptor class B type I (SR-BI) has been established as the primary mediator of the selective transfer of lipids from HDL to mammalian cells.
Kristin Gillotte-Taylor   +4 more
doaj   +3 more sources

Loss of Function of Scavenger Receptor SCAV-5 Protects C. elegans Against Pathogenic Bacteria

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Scavenger receptors play a critical role in innate immunity by acting as the pattern-recognition receptors. There are six class B scavenger receptors homologs in C. elegans.
Aixiao Luo   +5 more
doaj   +1 more source

A gut feeling for drugs that have metabolic benefits

open access: yesNature Communications, 2023
Resveratrol (REV) is a natural polyphenol with anti-obesity effects. However, the mechanisms remain unclear due to its low bioavailability and the lack of defined membrane-bound or nuclear receptors.
Eryun Zhang, Alon Agua, Wendong Huang
doaj   +1 more source

HSL-knockout mouse testis exhibits class B scavenger receptor upregulation and disrupted lipid raft microdomains[S]

open access: yesJournal of Lipid Research, 2012
There is a tight relationship between fertility and changes in cholesterol metabolism during spermatogenesis. In the testis, class B scavenger receptors (SR-B) SR-BI, SR-BII, and LIMP II mediate the selective uptake of cholesterol esters from HDL, which ...
María Emilia Casado   +8 more
doaj   +1 more source

Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI

open access: yesJournal of Lipid Research, 2007
Modified forms of LDL, including oxidized low density lipoprotein (OxLDL), contribute to macrophage lipid accumulation in the vessel wall. Despite the pathophysiological importance of uptake pathways for OxLDL, the molecular details of OxLDL endocytosis ...
Bing Sun   +5 more
doaj   +1 more source

Overflow phenomenon in serum lutein after supplementation: a systematic review supported with SNPs analyses [PDF]

open access: yesInternational Journal of Ophthalmology, 2021
Lutein, a type of carotenoids, is found to delay the onset and progression of age-related macular degeneration (AMD). Several lutein supplementation studies showed that after an initial increase, lutein serum levels demonstrated a subsequent decrease ...
Abdulrahman M Alharbi   +2 more
doaj   +1 more source

ApoA-II modulates the association of HDL with class B scavenger receptors SR-BI and CD36

open access: yesJournal of Lipid Research, 2004
The class B scavenger receptors SR-BI and CD36 exhibit a broad ligand binding specificity. SR-BI is well characterized as a HDL receptor that mediates selective cholesteryl ester uptake from HDL.
Maria C. de Beer   +5 more
doaj   +1 more source

Innovation in Nucleotide-Binding Oligomerization-Like Receptor and Toll-Like Receptor Sensing Drives the Major Histocompatibility Complex-II Free Atlantic Cod Immune System

open access: yesFrontiers in Immunology, 2020
The absence of MHC class II antigen presentation and multiple pathogen recognition receptors in the Atlantic cod has not impaired its immune response however how underlying mechanisms have adapted remains largely unknown.
Xingkun Jin   +9 more
doaj   +1 more source

MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis.

open access: yesPLoS Pathogens, 2009
Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro-inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be induced by its predominant cell wall glycolipid, trehalose 6,6 ...
Dawn M E Bowdish   +8 more
doaj   +1 more source

Contribution of Glycation and Oxidative Stress to Thyroid Gland Pathology—A Pilot Study

open access: yesBiomolecules, 2021
The patho-mechanism of changes in the thyroid gland, including carcinogenesis, is a complex process, which involves oxidative stress. The goal of our investigation was to verify the extent of stress in the thyroid gland related to glycation.
Aleksandra Kuzan   +8 more
doaj   +1 more source

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