Results 1 to 10 of about 486,419 (221)
Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein [PDF]
Journal of Lipid Research, 2001 Scavenger receptor class B type I (SR-BI) has been established as the primary mediator of the selective transfer of lipids from HDL to mammalian cells.
Kristin Gillotte-Taylor +4 more
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Loss of Function of Scavenger Receptor SCAV-5 Protects C. elegans Against Pathogenic Bacteria
Frontiers in Cellular and Infection Microbiology, 2021 Scavenger receptors play a critical role in innate immunity by acting as the pattern-recognition receptors. There are six class B scavenger receptors homologs in C. elegans.
Aixiao Luo +5 more
doaj +1 more source
Scavenger receptor class B type I: a multifunctional receptor [PDF]
Annals of the New York Academy of Sciences, 2011 The scavenger receptor class B type I (SR‐B1) plays an important role in meditating the uptake of HDL‐derived cholesterol and cholesteryl ester in the liver and steroidogenic tissues. In addition to being ubiquitous, SR‐B1 is a high‐density lipoprotein (HDL) receptor in many tissues, though the mechanism by which SR‐B1 does this is unclear.
Alessandra Pecorelli +4 more
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The class A scavenger receptor SR-A/CD204 and the class B scavenger receptor CD36 regulate immune functions of macrophages differently [PDF]
Innate Immunity, 2013 SR-A/CD204 and CD36 are major receptors responsible for oxidized lipoproteins uptake by macrophages in atherosclerotic plaques. Both receptors also share the role as receptors for different pathogens, but studies on their signaling have been hampered by the lack of selective ligands.
Józefowski, Szczepan +4 more
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Regulation of Platelet Function by Class B Scavenger Receptors in Hyperlipidemia [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2010 Platelets constitutively express class B scavenger receptors CD36 and SR-BI, 2 closely related pattern recognition receptors best known for their roles in lipoprotein and lipid metabolism. The biological role of scavenger receptors in platelets is poorly understood.
Alejandro Zimman, Eugene A. Podrez
openaire +2 more sources
A gut feeling for drugs that have metabolic benefits
Nature Communications, 2023 Resveratrol (REV) is a natural polyphenol with anti-obesity effects. However, the mechanisms remain unclear due to its low bioavailability and the lack of defined membrane-bound or nuclear receptors.
Eryun Zhang, Alon Agua, Wendong Huang
doaj +1 more source
The Class B Scavenger Receptors SR-BI and CD36 Are Receptors for Anionic Phospholipids [PDF]
Journal of Biological Chemistry, 1995 The specific recognition of anionic phospholipids in the outer leaflets of cell membranes and lipoproteins by cell surface receptors may play an important role in a variety of physiologic and pathophysiologic processes (e.g. recognition of damaged or senescent cells by the reticuloendothelial system or lipoprotein homeostasis).
Susan L. Acton +2 more
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Sterol regulation of scavenger receptor class B type I in macrophages [PDF]
Journal of Lipid Research, 2004 Scavenger receptor class B type I (SR-BI) is expressed in macrophages, but its role in sterol trafficking in these cells remains controversial. We examined the effect of sterol loading on SR-BI expression in human monocytes/macrophages, mouse peritoneal macrophages, and a cultured mouse macrophage cell line (J774 cells).
Guoqing Cao +4 more
openaire +3 more sources
Overflow phenomenon in serum lutein after supplementation: a systematic review supported with SNPs analyses [PDF]
International Journal of Ophthalmology, 2021 Lutein, a type of carotenoids, is found to delay the onset and progression of age-related macular degeneration (AMD). Several lutein supplementation studies showed that after an initial increase, lutein serum levels demonstrated a subsequent decrease ...
Abdulrahman M Alharbi +2 more
doaj +1 more source
Frontiers in Immunology, 2020 The absence of MHC class II antigen presentation and multiple pathogen recognition receptors in the Atlantic cod has not impaired its immune response however how underlying mechanisms have adapted remains largely unknown.
Xingkun Jin +9 more
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