Results 11 to 20 of about 22,858 (247)
Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity. [PDF]
Amino Acids, 2017 The EF-hand type calcium-binding protein S100A12 exerts numerous intra- and extracellular functions of (patho)physiological relevance. Therefore, receptors of S100A12 are of high interest for research and clinical applications. Beside the extensively studied receptor for advanced glycation endproducts (RAGE), G-protein coupled receptors and more ...
Tondera C, Laube M, Pietzsch J.
europepmc +5 more sources
Scavenger receptor class B type I: a multifunctional receptor [PDF]
Annals of the New York Academy of Sciences, 2011 The scavenger receptor class B type I (SR‐B1) plays an important role in meditating the uptake of HDL‐derived cholesterol and cholesteryl ester in the liver and steroidogenic tissues. In addition to being ubiquitous, SR‐B1 is a high‐density lipoprotein (HDL) receptor in many tissues, though the mechanism by which SR‐B1 does this is unclear.
VALACCHI, Giuseppe +3 more
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Scavenger receptor class B, type 1 facilitates cellular fatty acid uptake [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2020 SR-B1 belongs to the class B scavenger receptor, or CD36 super family. SR-B1 and CD36 share an affinity for a wide array of ligands. Although they exhibit similar ligand binding specificity, SR-B1 and CD36 have some very specific lipid transport functions.
Wei, Wang +5 more
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Dimerization of the scavenger receptor class B type I [PDF]
Journal of Lipid Research, 2004 This study has examined the dimeric/oligomeric forms of scavenger receptor class B type I (SR-BI) and its alternatively spliced form, SR-BII, in a diverse group of cells and tissues: i.e., normal and hormonally altered tissues of mice and rats as well as tissues of transgenic animals and genetically altered steroidogenic and nonsteroidogenic cells ...
Eve Reaven +4 more
openaire +2 more sources
Journal of Lipid Research, 2009 To learn more about how the step of cholesterol uptake into the brush border membrane (BBM) of enterocytes influences overall cholesterol absorption, we measured cholesterol absorption 4 and 24 h after administration of an intragastric bolus of ...
David V. Nguyen +5 more
doaj +1 more source
Advanced glycation end products and their receptors in serum of patients with type 2 diabetes
Scientific Reports, 2021 Glycation is a non-enzymatic process involving the reaction of reducing sugars or reactive oxoaldehyde with proteins, lipids or nucleic acids, which results in the formation of advanced glycation end products (AGEs).
Diana Indyk +3 more
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The Past and Present Lives of the Intraocular Transmembrane Protein CD36
Cells, 2022 Cluster of differentiation 36 (CD36) belongs to the B2 receptors of the scavenger receptor class B family, which is comprised of single-chain secondary transmembrane glycoproteins.
Rucui Yang, Qingping Liu, Mingzhi Zhang
doaj +1 more source
Journal of Lipid Research, 1999 In addition to its effect on high density lipoprotein (HDL) cholesteryl ester (CE) uptake, scavenger receptor BI (SR-BI) was recently reported to stimulate free cholesterol (FC) flux from Chinese hamster ovary (CHO) cells stably expressing mouse SR-BI, a
Margarita de la Llera-Moya +6 more
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Sterol regulation of scavenger receptor class B type I in macrophages [PDF]
Journal of Lipid Research, 2004 Scavenger receptor class B type I (SR-BI) is expressed in macrophages, but its role in sterol trafficking in these cells remains controversial. We examined the effect of sterol loading on SR-BI expression in human monocytes/macrophages, mouse peritoneal macrophages, and a cultured mouse macrophage cell line (J774 cells).
Liqing Yu +3 more
openaire +3 more sources
Targeting SR-BI for cancer diagnostics, imaging and therapy
Frontiers in Pharmacology, 2016 Scavenger receptor class B type I (SR-BI) plays an important role in trafficking cholesteryl esters between the core of high density lipoprotein and the liver. Interestingly, this integral membrane protein receptor is also implicated in the metabolism of
Maneesha Amrita Rajora +4 more
doaj +1 more source