Results 11 to 20 of about 486,419 (221)
Contribution of Glycation and Oxidative Stress to Thyroid Gland Pathology—A Pilot Study
Biomolecules, 2021 The patho-mechanism of changes in the thyroid gland, including carcinogenesis, is a complex process, which involves oxidative stress. The goal of our investigation was to verify the extent of stress in the thyroid gland related to glycation.
Aleksandra Kuzan +8 more
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Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity [PDF]
Amino Acids, 2016 The EF-hand type calcium-binding protein S100A12 exerts numerous intra- and extracellular functions of (patho)physiological relevance. Therefore, receptors of S100A12 are of high interest for research and clinical applications. Beside the extensively studied receptor for advanced glycation endproducts (RAGE), G-protein coupled receptors and more ...
Christoph Tondera +2 more
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PLoS Pathogens, 2009 Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro-inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be induced by its predominant cell wall glycolipid, trehalose 6,6 ...
Dawn M E Bowdish +8 more
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Advanced glycation end products and their receptors in serum of patients with type 2 diabetes
Scientific Reports, 2021 Glycation is a non-enzymatic process involving the reaction of reducing sugars or reactive oxoaldehyde with proteins, lipids or nucleic acids, which results in the formation of advanced glycation end products (AGEs).
Diana Indyk +3 more
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The Past and Present Lives of the Intraocular Transmembrane Protein CD36
Cells, 2022 Cluster of differentiation 36 (CD36) belongs to the B2 receptors of the scavenger receptor class B family, which is comprised of single-chain secondary transmembrane glycoproteins.
Rucui Yang, Qingping Liu, Mingzhi Zhang
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CD36, a Member of the Class B Scavenger Receptor Family, as a Receptor for Advanced Glycation End Products [PDF]
Journal of Biological Chemistry, 2001 Abstract: Interaction of advanced glycation end products (AGE) with AGE‐receptors induces several cellular phenomena relating potentially to diabetic complications. Five AGE‐receptors identified so far are RAGE (receptor for AGE), 80 K‐H, OST‐48, galectin‐3, and SR‐A (macrophage scavenger receptor type I and II).
Seikoh Horiuchi +6 more
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A class B scavenger receptor mediates the cellular uptake of carotenoids in Drosophila [PDF]
Proceedings of the National Academy of Sciences, 2002 Carotenoids are currently being intensely investigated regarding their potential to lower the risk of chronic disease and vitamin A deficiency. Invertebrate models in which vitamin A deficiency is not lethal allow the isolation of blind but viable mutants affected in the pathway leading from dietary carotenoids to vitamin A. Using a mutant
Mathias F. Wernet +3 more
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Dimerization of the scavenger receptor class B type I [PDF]
Journal of Lipid Research, 2004 This study has examined the dimeric/oligomeric forms of scavenger receptor class B type I (SR-BI) and its alternatively spliced form, SR-BII, in a diverse group of cells and tissues: i.e., normal and hormonally altered tissues of mice and rats as well as tissues of transgenic animals and genetically altered steroidogenic and nonsteroidogenic cells ...
Yuan Cortez +5 more
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Targeting SR-BI for cancer diagnostics, imaging and therapy
Frontiers in Pharmacology, 2016 Scavenger receptor class B type I (SR-BI) plays an important role in trafficking cholesteryl esters between the core of high density lipoprotein and the liver. Interestingly, this integral membrane protein receptor is also implicated in the metabolism of
Maneesha Amrita Rajora +4 more
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Scavenger receptor class B type I localizes to a late endosomal compartment [PDF]
Journal of Lipid Research, 2008 Scavenger receptor class B type I (SR-BI) has an established role in mediating the selective uptake of cholesterol from HDL in hepatocytes, steroidogenic cells, and other tissues. SR-BI is present on the plasma membrane but also localizes to stable intracellular compartments of unknown function.
Thet Naing, Ruth McPherson, Malika Ahras
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