Results 21 to 30 of about 22,858 (247)
Targeting Early Dementia: Using Lipid Cubic Phase Nanocarriers to Cross the Blood–Brain Barrier
Biomimetics, 2018 Over the past decades, a frequent co-morbidity of cerebrovascular pathology and Alzheimer’s disease has been observed. Numerous published studies indicate that the preservation of a healthy cerebrovascular endothelium can be an important therapeutic ...
Joseph S. D’Arrigo
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Frontiers in Microbiology, 2012 Enterovirus 71 (EV71) is one of the major causative agents of hand, foot and mouth disease (HFMD). Infection with EV71 is occasionally associated with severe neurological diseases such as acute encephalitis, acute flaccid paralysis and cardiopulmonary ...
Seiya eYamayoshi +2 more
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Regulation of Platelet Function by Class B Scavenger Receptors in Hyperlipidemia [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2010 Platelets constitutively express class B scavenger receptors CD36 and SR-BI, 2 closely related pattern recognition receptors best known for their roles in lipoprotein and lipid metabolism. The biological role of scavenger receptors in platelets is poorly understood.
Alejandro, Zimman, Eugene A, Podrez
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Transcriptional Regulation of Rat Scavenger Receptor Class B Type I Gene [PDF]
Journal of Biological Chemistry, 2000 The scavenger receptor class B type I (SR-BI) mediates the selective transport of lipids from high density lipoprotein to cells and plays an important role in the reverse uptake of cholesterol to the liver and in the delivery of substrates for steroidogenesis in steroidogenic organs.
T, Mizutani +3 more
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SR-BI-directed HDL-cholesteryl ester hydrolysis
Journal of Lipid Research, 2003 We have examined the metabolic fate of HDL cholesteryl ester (CE) delivered to cells expressing scavenger receptor class B type I (SR-BI). Comparison of SR-BI with a related class B scavenger receptor, CD36, showed a greater uptake and a more rapid and ...
Margery A. Connelly +3 more
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Soluble CD5 and CD6: Lymphocytic Class I Scavenger Receptors as Immunotherapeutic Agents
Cells, 2020 CD5 and CD6 are closely related signal-transducing class I scavenger receptors mainly expressed on lymphocytes. Both receptors are involved in the modulation of the activation and differentiation cell processes triggered by clonotypic antigen-specific ...
María Velasco-de Andrés +5 more
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The class A scavenger receptor SR-A/CD204 and the class B scavenger receptor CD36 regulate immune functions of macrophages differently [PDF]
Innate Immunity, 2013 SR-A/CD204 and CD36 are major receptors responsible for oxidized lipoproteins uptake by macrophages in atherosclerotic plaques. Both receptors also share the role as receptors for different pathogens, but studies on their signaling have been hampered by the lack of selective ligands.
Józefowski, Szczepan +4 more
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Medical Sciences, 2017 Owing to the complexity of neurodegenerative diseases, multiple cellular types need to be targeted simultaneously in order for a given therapy to demonstrate any major effectiveness.
Joseph S. D’Arrigo
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Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus. [PDF]
PLoS Pathogens, 2016 Scavenger receptor class B type 1 (SR-B1) and low-density lipoprotein receptor (LDLR) are known to be involved in entry of hepatitis C virus (HCV), but their precise roles and their interplay are not fully understood. In this study, deficiency of both SR-
Satomi Yamamoto +14 more
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CD36 does not play a direct role in HDL or LDL metabolism
Journal of Lipid Research, 2001 CD36 and scavenger receptor class B, type I (SR-BI) are both class B scavenger receptors that recognize a broad variety of ligands, including oxidized low density lipoprotein (oxLDL), HDL, anionic phospholipids, and apoptotic cells.
Willem J.S. de Villiers +5 more
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