Results 151 to 160 of about 12,357,672 (189)

Schisandrin B protects against solar irradiation-induced oxidative stress in rat skin tissue

Fìtoterapìâ, 2011
Schisandrin B (Sch B) and schisandrin C (Sch C), but not schisandrin A and dimethyl diphenyl bicarboxylate, protected rat skin tissue against solar irradiation-induced oxidative injury, as evidenced by a reversal of solar irradiation-induced changes in ...
Hoi Yan Leung, Kam Ming Ko, Po Yee Chiu
exaly   +2 more sources

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Inhibitory effects of schisandrin A and schisandrin B on CYP3A activity

Methods and Findings in Experimental and Clinical Pharmacology, 2010
Our aim was to investigate the inhibitory effects of schisandrin A and schisandrin B on cytochrome P450 (CYP3A) activity in rat liver microsomes and the mechanism of this interaction. 1'-Hydroxy midazolam and midazolam 1-hydroxylation catalyzed by CYP3A were analyzed by high performance liquid chromatography (HPLC).
W L, Li, H W, Xin, M W, Su, L, Xiong
openaire   +2 more sources

Comparative Effects of Schisandrin A, B, and C on Acne-Related Inflammation

Inflammation, 2017
Inflammatory responses induced by Propionibacterium acnes are a major etiological factor in the pathogenesis of acne vulgaris. Schisandrin A, schisandrin B, and schisandrin C are the representative lignans of Schisandra chinensis (Turcz.) Baill. extract.
Faliang An, Yanhua Lu, Miaomiao Guo
exaly   +3 more sources

Schisandrin B promotes TH1 cell differentiation by targeting STAT1

International Immunopharmacology, 2021
Schisandrin B (Sch B) is the major active ingredient of the traditional Chinese medicine Schisandra chinensis and has antitumor activity, anti-inflammatory activity. CD4+ Th subsets orchestrate immune responses to plenty of pathogen infections and participate in the pathogenesis of many immune-related diseases.
Jufeng Guo, Yingying Shen, Xia Lin, Honggang Chen, Jian Liu   +4 more
openaire   +2 more sources

Schisandrin B and Other Dibenzocyclooctadiene Lignans

2004
Schisandrin B (Sch B, Fig. 1a) is the most abundant dibenzocyclooctadiene derivative (lignan) isolated from Fructus Schisandrae (FS), the fruit of Schisandra chinensis (Turcz.) Baillon, or Wu-Wei-Zi, meaning the fruit of five tastes in Chinese. FS is a commonly used herb in traditional Chinese medicine (TCM).
Robert Kam-Ming Ko, Duncan Mak
openaire   +2 more sources

Schisandrin A and B affect the proliferation and differentiation of neural stem cells

Journal of Chemical Neuroanatomy, 2022
Schisandrin A and B (Sch A and B) are the important components of Asian dietary supplement and phytomedicine Schisandra chinensis (S. chinensis). They can enhance adult neurogenesis in vivo; however, these effects still need to be verified. Here NE-4 C neural stem cells (NSCs) were employed as the in vitro model and treated with Sch A and B at 0.1 μg ...
Ning-Ning, Cai, Qi, Geng, Yu, Jiang, Wen-Qian, Zhu, Rui, Yang, Bo-Yang, Zhang, Yu-Feng, Xiao, Bo, Tang, Xue-Ming, Zhang   +8 more
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Schisandrin A and B enhance the dentate gyrus neurogenesis in mouse hippocampus

Journal of Chemical Neuroanatomy, 2020
Schisandrin A and B (Sch A and B) are the main effective components of Schisandra chinensis (S. chinensis), which is traditionally used to enhance mental and intellectual functions in eastern Asia. Previously, we reported Sch A and B remarkably affect adult neurogenesis in the subventricular zone of mouse lateral ventricle.
Ning-Ning Cai, Zheng-Zhu Wang, Xian-Chun Zhu, Yu Jiang, Wen-Qian Zhu, Rui Yang, Xue-Ming Zhang   +6 more
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Schisandrin A and B affect subventricular zone neurogenesis in mouse

European Journal of Pharmacology, 2014
Schisandrin A and B (Sch A and B) are the main effective components extracted from the oriental medicine Schisandra chinensis which is traditionally used to enhance mental and intellectual function. Although their neuroprotective effects have been demonstrated, their influences on neurogenesis are still unknown.
Yi-Xue, Sun, Yan-Long, Cong, Yang, Liu, Bo, Jin, Lu, Si, Ai-Bing, Wang, Huan, Cai, Guan-Yu, Che, Bo, Tang, Chun-Feng, Wang, Zi-Yi, Li, Xue-Ming, Zhang   +11 more
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The synergistic anti-tumor effect of schisandrin B and apatinib

Journal of Asian Natural Products Research, 2019
The synergistic anti-tumor effect of schisandrin B (Sch.B) and apatinib was investigated in vitro. The CCK-8 assay revealed that Sch.B enhanced the inhibition of apatinib on cell proliferation by arresting cell cycle in G0/G1 phase. Sch.B also potentiated the suppression of apatinib on cell migration and invasion, by means of wound-healing and ...
Ya-Jing Li, Hong-Tao Liu, Chao-Jun Xue, Xiao-Qin Xing, Song-Tao Dong, Lin-Shan Wang, Cong-Yang Ding, Lu Meng, Zhan-Jun Dong   +8 more
openaire   +2 more sources

The Protective Effects of Tea Polyphenols and Schisandrin B on Nephrotoxicity of Mercury

Biological Trace Element Research, 2011
Mercury (Hg) is an occupational and environmental contaminant that is a well-recognized health hazard. To approach the concrete mechanisms of mercury nephrotoxicity and find out a new way to prevent it, the rats were subcutaneously injected with different dosages of mercuric chloride (HgCl(2))--0, 2.2, 4.4, and 8.8 μmol/kg. The levels of Hg, blood urea
Wei, Liu, Zhaofa, Xu, Haibo, Yang, Yu, Deng, Bin, Xu, Yangang, Wei   +5 more
openaire   +2 more sources