Results 31 to 40 of about 7,401 (261)

Conversation and Argumentation in Boyle’s Scientific Dialogue [PDF]

open access: yesArmenian Folia Anglistika, 2014
The aim of this paper is to illustrate the new stylistic approach embodied in the genre of the scientific dialogue as used in 17th-century England, focusing, in particular, on the strategies adopted by Robert Boyle in The Sceptical Chymist (1661).
openaire   +3 more sources

An Argumentative Agent-Based Model of Scientific Inquiry [PDF]

open access: yes, 2017
In this paper we present an agent-based model (ABM) of scientific inquiry aimed at investigating how different social networks impact the efficiency of scientists in acquiring knowledge. As such, the ABM is a computational tool for tackling issues in the domain of scientific methodology and science policy.
Annemarie Borg   +3 more
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Discourse-Driven Argument Mining in Scientific Abstracts [PDF]

open access: yes, 2019
Argument mining consists in the automatic identification of argumentative structures in texts. In this work we address the open question of whether discourse-level annotations can contribute to facilitate the identification of argumentative components and relations in scientific literature.
Pablo Accuosto, Horacio Saggion
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Scientific Reasoning and Argumentation: Advancing an Interdisciplinary Research Agenda in Education

open access: yesFrontline Learning Research, 2014
Scientific reasoning and scientific argumentation are highly valued outcomes of K-12 and higher education. In this article, we first review main topics and key findings of three different strands of research, namely research on the development of ...
Frank Fischer   +12 more
doaj   +1 more source

Development of Newton Gravity Student Worksheets on Problem-Based Learning Model to Improve Students' Scientific Argumentation Skills

open access: yesPrisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram, 2022
The purpose of this study was to evaluate the validity, practicability, and efficiency of student worksheets for improving students' scientific argumentation skills on the topic of Newton's Law of Gravity.
Dhila Linggar Lentika, Setyo Admoko
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The Effectiveness of Scientific Argumentation Strategy towards the Various Learning Outcomes and Educational Levels Five Over the Years in Science Education

open access: yesJournal of Innovation in Educational and Cultural Research, 2020
This study aimed to investigate the effectiveness of scientific argumentation strategy towards various learning outcomes and educational levels five over the years in science education.
Indah Juwita Sari   +1 more
doaj   +1 more source

Scientific arguments in policy-making [PDF]

open access: yesJournal of Argumentation in Context, 2019
Abstract This paper focuses on the use of scientific insights for justifying decisions in policy-making. Because in policy-making the politician argues for a future course of action by pointing at its positive consequences, the burden of proof should concern not only the ...
Andone, C., Lomeli Hernández, J.A.
openaire   +4 more sources

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