SOCS3 inhibits the mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic mice [PDF]
Stem Cell Research & Therapy, 2023 Background Islet transplantation is used therapeutically in a minority of patients with type 1 diabetes (T1D). However, successful outcomes are hampered by early islet β-cell loss caused by immune rejection and autoimmunity.
Mingxing Sui +7 more
doaj +2 more sources
SDF-1 alleviates osteoarthritis by resolving mitochondrial dysfunction through the activation of the Sirt3/PGC-1α signalling pathway [PDF]
Arthritis Research & TherapyObjective Osteoarthritis (OA) is the most common form of joint disease. Currently, OA treatment is limited to controlling symptoms. Our previous study showed that stromal cell-derived factor 1 (SDF-1) delayed the progression of OA to a certain extent ...
Yanping Zhao +8 more
doaj +2 more sources
Bone Reports, 2019 Our previous studies showed that in a mouse model in which PI3K-AKT activation was increased (YF mice), osteoclast numbers and levels of SDF-1, a chemokine, were augmented.
Naga Suresh Adapala +4 more
doaj +3 more sources
The effects of SDF-1 combined application with VEGF on femoral distraction osteogenesis in rats [PDF]
Open Life SciencesBone regeneration and mineralization can be achieved by means of distraction osteogenesis (DO). In the present study, we investigated the effect of stromal cell-derived factor 1 (SDF-1) and vascular endothelial growth factor (VEGF) on the new bone ...
Fu Fangang +8 more
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Author Correction: Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migration. [PDF]
Sci Rep, 2022 Chen D +8 more
europepmc +3 more sources
Higher Plasma Stromal Cell-Derived Factor 1 Is Associated with Lower Risk for Sarcopenia in Older Asian Adults [PDF]
Endocrinology and Metabolism, 2023 Background Despite the protective effects of stromal cell-derived factor 1 (SDF-1) in stimulating muscle regeneration shown in experimental research, there is a lack of clinical studies linking circulating SDF-1 concentrations with muscle phenotypes.
Sunghwan Ji +9 more
doaj +1 more source
Transcriptome analysis reveals the mechanism of stromal cell-derived factor-1 and exendin-4 synergistically promoted periodontal ligament stem cells osteogenic differentiation [PDF]
PeerJ, 2021 Stromal cell-derived factor-1 (SDF-1) and Exendin-4 (EX-4) play beneficial roles in promoting periodontal ligament stem cells (PDLSCs) osteogenic differentiation, while the detailed mechanism has not been clarified.
Wenyan Kang +5 more
doaj +2 more sources
Stromal cell-derived factor 1 regulates the actin organization of chondrocytes and chondrocyte hypertrophy. [PDF]
PLoS ONE, 2012 Stromal cell-derived factor 1 (SDF-1/CXCL12/PBSF) plays important roles in the biological and physiological functions of haematopoietic and mesenchymal stem cells.
Koichi Murata +12 more
doaj +1 more source
Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migration [PDF]
Scientific Reports, 2015 AbstractStromal cell-derived factor 1 (SDF-1) is a chemokine that can be expressed in injured cardiomyocytes after myocardial infarction (MI). By combining with its receptor CXCR4, SDF-1 induced stem and progenitor cells migration. CXCR7, a novel receptor for SDF-1, has been identified recently.
Dong Chen +8 more
openaire +3 more sources
Radiographic Changes to Silver Diamine Fluoride Treated Carious Lesions after a Rinsing Step
Dentistry Journal, 2022 Silver diamine fluoride (SDF) is radiopaque. This in vitro study compares the changes in the radiopacity of carious lesions after SDF application, potassium iodide (PI) application, and water rinse.
Zaher Jabbour +3 more
doaj +1 more source