Results 21 to 30 of about 43,872 (217)
CXCL12 (SDF-1)/CXCR4 Pathway in Cancer [PDF]
Clinical Cancer Research, 2010 Abstract Chemokines, small proinflammatory chemoattractant cytokines that bind to specific G-protein-coupled seven-span transmembrane receptors, are major regulators of cell trafficking and adhesion. The chemokine CXCL12 [stromal cell-derived factor-1 (SDF-1)] binds primarily to CXC receptor 4 (CXCR4; CD184).
Beverly A, Teicher, Simon P, Fricker
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Upregulation of stromal cell-derived factor 1 (SDF-1) is associated with macrophage infiltration in renal ischemia-reperfusion injury. [PDF]
PLoS ONE, 2014 Stromal cell-derived factor-1(SDF-1) is a chemotactic and angiogenic factor that mediates the repair of various tissues. As macrophages are important contributors to ischemic kidney injury, we examine the role of SDF-1 in a rodent model of ischemia ...
Xin Wan +6 more
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A Novel CXCR4 Targeting Protein SDF-1/54 as an HIV-1 Entry Inhibitor
Viruses, 2019 CXC chemokine receptor 4 (CXCR4) is a co-receptor for HIV-1 entry into target cells. Its natural ligand, the chemokine SDF-1, inhibits viral entry mediated by this receptor. However, the broad expression pattern of CXCR4 and its critical roles in various
Suiyi Tan +13 more
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Stem Cell Research & Therapy, 2023 Background Islet transplantation is used therapeutically in a minority of patients with type 1 diabetes (T1D). However, successful outcomes are hampered by early islet β-cell loss caused by immune rejection and autoimmunity.
Mingxing Sui +7 more
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Histological Examination of Engineered Mesenchymal Stem Cells Improve Bladder Function in Rat
Korean Journal of Clinical Laboratory Science, 2020 This study was undertaken to examine the effects and to investigate the relevant mechanisms of overexpressing stromal cell-derived factor-1 (SDF-1) produced by engineered mesenchymal stem cells, in a neurogenic bladder (NB) rat model. Sprague-Dawley (SD)
Eun Kyung Cho, Seung Hwan Jeon
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Platelets, 2022 Stromal cell-derived factor 1 (SDF-1, also known as CXCL12) and its receptor CXCR4 have shown to play a role in the homing and engraftment of hematopoietic stem and progenitor cells.
Yi Li +5 more
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Cell Transplantation, 2010 Proper wound diagnosis and management is an increasingly important clinical challenge and is a large and growing unmet need. Pressure ulcers, hard-to-heal wounds, and problematic surgical incisions are emerging at increasing frequencies.
Sina Y. Rabbany +6 more
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Functional diversity of SDF-1 splicing variants [PDF]
Cell Adhesion & Migration, 2009 SDF-1 is ubiquitously expressed in vertebrate tissues in a constitutive manner. It performs an essential role in cell migration and proliferation as well as participates in tissue-specific physiological processes such as neuromodulation. It is also involved in many pathological processes including: HIV infection, metastatic malignancy, chronic ...
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Dentistry Journal, 2023 Background: Restoring bonding composite to silver diamine fluoride (SDF)-treated enamel is challenging. This study investigates if phosphoric acid etch restores composite bond strength to SDF-treated enamel using universal adhesives. Methods: Twenty-four
Zaher Jabbour +3 more
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Journal of Biomedical Science, 2012 Background The CXC chemokine ligand 12 (CXCL12)/stromal cell-derived factor-1 (SDF-1) and CXC receptor 4 (CXCR4) axis is involved in human colorectal cancer (CRC) carcinogenesis and can promote the progression of CRC.
Tung Shui-Yi +7 more
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