Results 11 to 20 of about 20,702 (201)

Selenoprotein: Potential Player in Redox Regulation in Chlamydomonas reinhardtii

Antioxidants, 2022
Selenium (Se) is an essential micro-element for many organisms, including Chlamydomonas reinhardtii, and is required in trace amounts. It is obtained from the 21st amino acid selenocysteine (Sec, U), genetically encoded by the UGA codon.
Sandip A. Ghuge, Ulhas Sopanrao Kadam, Jong Chan Hong   +2 more
doaj   +1 more source

Optimized methyl donor and reduced precursor degradation pathway for seleno-methylselenocysteine production in Bacillus subtilis

Microbial Cell Factories, 2023
Background Seleno-methylselenocysteine (SeMCys) is an effective component of selenium supplementation with anti-carcinogenic potential that can ameliorate neuropathology and cognitive deficits.
Xian Yin, Meiyi Zhao, Yu Zhou, Hulin Yang, Yonghong Liao, Fenghuan Wang   +5 more
doaj   +1 more source

Environmental and Circadian Regulation Combine to Shape the Rhythmic Selenoproteome

Cells, 2022
The circadian clock orchestrates an organism’s endogenous processes with environmental 24 h cycles. Redox homeostasis and the circadian clock regulate one another to negate the potential effects of our planet’s light/dark cycle on the generation of ...
Holly Kay, Harry Taylor, Gerben van Ooijen   +2 more
doaj   +1 more source

Selenocysteine Machinery Primarily Supports TXNRD1 and GPX4 Functions and Together They Are Functionally Linked with SCD and PRDX6

Biomolecules, 2022
The human genome has 25 genes coding for selenocysteine (Sec)-containing proteins, whose synthesis is supported by specialized Sec machinery proteins.
Didac Santesmasses, Vadim N. Gladyshev
doaj   +1 more source

Theoretical Investigations on the Sensing Mechanism of Phenanthroimidazole Fluorescent Probes for the Detection of Selenocysteine

Molecules, 2022
The level of selenocysteine (Sec) in the human body is closely related to a variety of pathophysiological states, so it is important to study its fluorescence sensing mechanism for designing efficient fluorescent probes.
Zhe Tang, Xiaochen Wang, Runze Liu, Panwang Zhou   +3 more
doaj   +1 more source

Chlorophyllin Inhibits Mammalian Thioredoxin Reductase 1 and Triggers Cancer Cell Death

Antioxidants, 2021
Food colorants are widely used by humans in food production and preparation; however, their potential toxicity requires an in-depth analysis. In this study, five out of 15 commercial food colorants, namely, lutein, betanin, caramel, crocin and ...
Shibo Sun, Yici Zhang, Weiping Xu, Yue Zhang, Rui Yang, Jianli Guo, Shui Guan, Qiang Ma, Kun Ma, Jianqiang Xu   +9 more
doaj   +1 more source

Indirect Routes to Aminoacyl-tRNA: The Diversity of Prokaryotic Cysteine Encoding Systems

Frontiers in Genetics, 2022
Universally present aminoacyl-tRNA synthetases (aaRSs) stringently recognize their cognate tRNAs and acylate them with one of the proteinogenic amino acids.
Takahito Mukai, Takahito Mukai, Kazuaki Amikura, Xian Fu, Dieter Söll, Dieter Söll, Ana Crnković, Ana Crnković   +7 more
doaj   +1 more source

Comparative analysis of CO2 reduction by soluble Escherichia coli formate dehydrogenase H and its selenocysteine-to-cysteine substitution variant

Journal of CO2 Utilization, 2023
Metal-dependent formate dehydrogenases (Me-FDHs) are highly active CO2-reducing enzymes operating at low redox potentials and employ either molybdenum or tungsten to reduce the bound substrate.
Feilong Li, Silvan Scheller, Michael Lienemann   +2 more
doaj   +1 more source

Selenoprotein gene nomenclature [PDF]

, 2016
The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis.
Arn\ue9r, Elias S., Berry, Marla J., Bruford, Elspeth A., Burk, Raymond F., Carlson, Bradley A., Castellano, Sergi, Chavatte, Laurent, Conrad, Marcus, Copeland, Paul R., Diamond, Alan M., Driscoll, Donna M., Ferreiro, Ana, Floh\ue9, Leopold, Gladyshev, Vadim N, Green, Fiona R., Guig\uf3, Roderic, Handy, Diane E., Hatfield, Dolph L., Hesketh, John, Hoffmann, Peter R., Holmgren, Arne, Hondal, Robert J., Howard, Michael T., Huang, Kaixun, K\uf6hrle, Josef, Kim, Hwa Young, Kim, Ick Young, Krol, Alain, Kryukov, Gregory V., Lee, Byeong Jae, Lee, Byung Cheon, Lei, Xin Gen, Lescure, Alain, Liu, Qiong, Lobanov, Alexei V., Loscalzo, Joseph, Maiorino, Matilde, Mariotti, Marco, Prabhu, K. Sandeep, Rayman, Margaret P., Regina, Brigelius Floh\ue9, Rozovsky, Sharon, Salinas, Gustavo, Schmidt, Edward E., Schomburg, Lutz, Schweizer, Ulrich, Simonovi\u107, Miljan, Sunde, Roger A., Tsuji, Petra A., Tweedie, Susan, Ursini, Fulvio, Whanger, Philip D., Zhang, Yan   +52 more
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Effects of selenium biofortification on crop nutritional quality [PDF]

, 2015
Selenium (Se) at very low doses has crucial functions in humans and animals. Since plants represent the main dietary source of this element, Se-containing crops may be used as a means to deliver Se to consumers (biofortification). Several strategies have
Dall'Acqua, Stefano, Elizabeth A. H., Pilon Smits, Malagoli, Mario, Schiavon, Michela   +3 more
core   +1 more source