Results 91 to 100 of about 10,333 (214)
Mouse models that target individual selenoproteins.
Selenium deficiency in humans or livestock and impaired selenoprotein synthesis in patients due to mutations in relevant genes have revealed the importance of selenoproteins for healthy life. Twenty-four genes for selenoproteins are encoded in the murine
Conrad, M. +3 more
core +1 more source
Selenoproteins across the tree of life: Methods and applications [PDF]
La selenocïsteina és coneguda com a l'aminoàcid 21. Les selenoproteïnes incorporen selenocïsteina en resposta a codons UGA específics mitjançant un mecanisme de recodificació, el qual és present en els tres dominis de la vida, però no en tots els ...
Santesmasses Ruiz, Didac
core +1 more source
The role of selenium in the pathogenesis of thyroid disease
The past few years have been actively discussing the role of individual macro- and micronutrients as factors regulating the functional activity of organs and systems and reducing the risk of developing a number of diseases, including thyroid diseases.
Ekaterina A. Troshina +2 more
doaj +1 more source
Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma +9 more
wiley +1 more source
Selenoproteins in colon cancer
Selenocysteine-containing proteins (selenoproteins) have been implicated in the regulation of various cell signaling pathways, many of which are linked to colorectal malignancies. In this in-depth excurse into the selenoprotein literature, we review possible roles for human selenoproteins in colorectal cancer, focusing on the typical hallmarks of ...
Kristin M, Peters +3 more
openaire +3 more sources
Selenoproteins in parasites [PDF]
Parasites, which cause an enormous burden in the population of the third world, are a diverse group of organisms, many of which are sensitive to oxidative stress imposed by their hosts.
Lobanov, Alexei V. +2 more
core
The findings highlight tissue‐specific responses to dietary selenium supplementation, with hepatic antioxidant modulation occurring without changes in plasma parameters, while selenium deposition patterns differed among tissues, emphasizing the complex relationship between selenium sources, metabolism, and antioxidant defense.
Diene France de de Souza +8 more
wiley +1 more source
Biological and Catalytic Properties of Selenoproteins
Selenocysteine is a catalytic residue at the active site of all selenoenzymes in bacteria and mammals, and it is incorporated into the polypeptide backbone by a co-translational process that relies on the recoding of a UGA termination codon into a serine/
Jean Chaudière
core +1 more source
Iron deficiency in heart failure: Epidemiology, diagnostic criteria and treatment modalities
ESC Heart Failure, Volume 12, Issue 2, Page 723-726, April 2025.
Stephan von Haehling
wiley +1 more source
Four novel 1,3‐selenazole‐2‐amine derivatives were synthesized and evaluated in HT‐29, MCF‐7, and L929 cell lines. Compound 4 showed the highest MCF‐7 cytotoxicity. Compound 3 displayed low L929 toxicity. In silico ADMET predicted favorable pharmacokinetic properties.
Gulay Dilek, Senem Akkoc
wiley +1 more source

