Results 71 to 80 of about 10,333 (214)
Stress and the Brain: An Emerging Role for Selenium
Frontiers in Neuroscience, 2021 The stress response is an important tool in an organism’s ability to properly respond to adverse environmental conditions in order to survive. Intense acute or chronic elevation of glucocorticoids, a class of stress hormone, can have deleterious ...
Daniel J. Torres +2 more
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Biological Reviews, EarlyView.ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley +1 more source
The Intrinsically Disordered Membrane Enzymes Selenoprotein S and Selenoprotein K [PDF]
Biophysical Journal, 2015 Selenoproteins constitute a family of enzymes involved in the management and regulation of reactive oxygen species, signaling molecules that are also affiliated with molecular damage and disease. The family contains two intrinsically disordered membrane proteins: selenoprotein S (SelS) and selenoprotein K (SelK). Both of these bitopic membrane proteins
Jun, Liu +2 more
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Chemistry – A European Journal, EarlyView.Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi +6 more
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“Alphabet” Selenoproteins: Implications in Pathology
, 2023 Selenoproteins are a group of proteins containing selenium in the form of selenocysteine (Sec, U) as the 21st amino acid coded in the genetic code. Their synthesis depends on dietary selenium uptake and a common set of cofactors.
Carmen Duță +3 more
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Role of selenium in the pathophysiology of cardiorenal anaemia syndrome
ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai +2 more
wiley +1 more source
Selenoproteins and Thyroid Cancer
, 2011 Selenoproteins, in which Se exists in the form of selenocysteine, are essential for protection against oxidative damage and cancer. Genetic data has provided evidence that reduced levels of these proteins, induced by loss of heterozygosity or chromosomal alterations [1], result in cellular oxidative stress as well as derangement of signaling cascades ...
Duntas, L.H., Smyth, P.P.A.
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HeliyonSelenium (Se), a component of selenoproteins and selenocompounds in the human body, is crucial for the development of male reproductive organs, DNA synthesis, thyroid hormone, metabolism, and defence against infections and oxidative damage. In the testis,
Shuai Yuan +8 more
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Antioxidants, 2019 The present work was part of a project intended to evaluate whether organic selenium (Se) has the potential to protect against toxic effects exerted by cadmium (Cd). For this reason, 300 as-hatched, one-day-old broiler chickens were randomly allocated in
Evangelos Zoidis +4 more
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iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
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