Sema3A secreted by sensory nerve induces bone formation under mechanical loads
Bone formation and deposition are initiated by sensory nerve infiltration in adaptive bone remodeling. Here, we focused on the role of Semaphorin 3A (Sema3A), expressed by sensory nerves, in mechanical loads-induced bone formation and nerve withdrawal ...
Hongxiang Mei +13 more
doaj +1 more source
Neuropilin 1 (NRP1) conveys SEMA3A signals to restrict physiological angiogenesis. [PDF]
Spreafico M +12 more
europepmc +2 more sources
Immunomodulatory cytoskeleton of bionic periosteum affects mitochondrial dynamics to promote osteogenesis. [PDF]
Zhou T +13 more
europepmc +1 more source
[<i>Wenyang Huazhuo Tongluo</i> Formula promotes angiogenesis in systemic sclerosis dermal microvascular endothelial cells by regulating the Sema3A/Nrp1 pathway]. [PDF]
Guo K +7 more
europepmc +1 more source
Diverse Roles of Semaphorins on T Cell Activation, Differentiation, Migration, and Effector Functions. [PDF]
Ma H, Gounni AS, Su RC, Kung SKP.
europepmc +1 more source
Slc1a2-mediated Glutamate Transport Promotes Dendritic Cell Immunity through Sema3A-regulated Cytoskeletal Remodeling and Migration. [PDF]
Chen S +8 more
europepmc +1 more source
GLP-1 receptor agonists alleviate inflammatory responses and endothelial dysfunction in atherosclerosis by activating the Sema3A/NRP1 pathway. [PDF]
Hu L +5 more
europepmc +1 more source
体外培养的大鼠皮层神经元氧糖剥夺后Sema3A;Nrp-1 mRNA表达上调与轴突网络损伤的关系
【目的】 研究体外培养的大鼠皮层神经元氧糖剥夺(OGD)处理后,Sema3A,Nrp-1 mRNA的表达变化及其与神经元轴突网络损伤的关系。【方法】 体外培养新生SD大鼠皮层神经元,随机分为正常对照组和OGD处理组:噻唑蓝(MTT)比色法测定神经元活性;βⅢ-tubulin免疫荧光染色观察轴突网络形态学变化,Real-time PCR 检测Sema3A及其受体Nrp-1 mRNA的表达;βⅢ-tubulin免疫荧光染色观察外源性Sema3A蛋白对神经元轴突生长的影响。【结果】 随着OGD时间的延长 ...
doaj
Complement C5a receptor 1 antagonist attenuates alveolar hypoplasia induced by pulmonary hypoperfusion and its underlying mechanisms. [PDF]
Liu C +12 more
europepmc +1 more source
Substitution of the SEMA3A basic domain with the VEGF<sub>165</sub> heparin-binding domain enhances anti-angiogenic potency in ovo. [PDF]
Valiulytė-Simaitė I +7 more
europepmc +1 more source

