Results 41 to 50 of about 2,098 (175)

A novel heterozygous intron mutation in SEMA7A causing kallmann syndrome in a female

Gynecological Endocrinology, 2019
Kallmann syndrome (KS) is a rare inherited disorder, which has significantly genotypic and phenotypic heterogeneity. KS is clinically characterized by the combination of hypogonadotropic hypogonadism and hypo/anosmia. At present, there is no relevant report that intron mutation in SEMA7A gene helps induce KS.
Yongting Zhao, Fan Yang, Lili Qiu, Lihong Wang, Hui Che   +4 more
openaire   +2 more sources

Comprehensive analysis of neuronal guidance cue expression regulation during monocyte-to-macrophage differentiation reveals post-transcriptional regulation of semaphorin7A by the RNA-binding protein quaking

Innate Immunity, 2021
In response to inflammatory cytokines and chemokines, monocytes differentiate into macrophages. Comprehensive analysis of gene expression regulation of neuronal guidance cue (NGC) ligands and receptors in the monocyte-to-macrophage differentiation ...
Huayu Zhang, Jurriën Prins, Dianne Vreeken, Barend W Florijn, Ruben G de Bruin, Oscar RJ van Hengel, Mieke F van Essen, Jacques MGJ Duijs, Hilde Van Esch, Eric P van der Veer, Anton Jan van Zonneveld, Janine M van Gils   +11 more
doaj   +1 more source

Association of Immune Semaphorins with COVID-19 Severity and Outcomes

Biomedicines, 2023
Semaphorins have recently been recognized as crucial modulators of immune responses. In the pathogenesis of COVID-19, the activation of immune responses is the key factor in the development of severe disease. This study aimed to determine the association
Martina Vargovic, Neven Papic, Lara Samadan, Mirjana Balen Topic, Adriana Vince   +4 more
doaj   +1 more source

Establishment of SEMA7A knockdown cells.

, 2015
(A) Expression of SEMA7A mRNA in shMock and shSEMA7A cells (SAS and KOSC-2-derived transfectants).
Isao Miyamoto (797074), Takane Suzuki (797075), Manabu Iyoda (359431), Yosuke Endo-Sakamoto (359437), Masashi Shiiba (281853), Atsushi Kasamatsu (281849), Hideki Tanzawa (145219), Kengo Saito (593605), Katsuhiro Uzawa (145207), Tomoaki Saito (797073), Katsunori Ogawara (281852)   +10 more
core   +1 more source

Evaluation of SEMA7A expression in OSCC-derived cell lines.

, 2015
(A) Quantification of SEMA7A mRNA expression in OSCC-derived cell lines by qRT-PCR analysis.
Isao Miyamoto (797074), Takane Suzuki (797075), Manabu Iyoda (359431), Yosuke Endo-Sakamoto (359437), Masashi Shiiba (281853), Atsushi Kasamatsu (281849), Hideki Tanzawa (145219), Kengo Saito (593605), Katsuhiro Uzawa (145207), Tomoaki Saito (797073), Katsunori Ogawara (281852)   +10 more
core   +1 more source

Regulation of SEMA7A during inflammation.

, 2016
Endothelial HMEC-1 and alveolar epithelial A549 cells were exposed to pro-inflammatory cytokines A) SEMA7A immunofluorescence in endothelial HMEC-1 following stimulation with TNF-α (100ng/ml) and IL-6 (20ng/ml) for 4 hours with SEMA7A (green), Actin (red)
Tiago Folgosa Granja (844738), David Köhler (147965), Peter Rosenberger (37609), Mariella Schneider (844737), Judith Marlene Roth (844736)   +4 more
core   +1 more source

SEMA7A is induced during lung injury.

, 2016
Lungs from WT animals were harvested 4 hours after exposure to either NaCl or LPS inhalation. A) Relative mRNA of SEMA7A in lung tissue determined by qPCR following LPS inhalation (n≥5/group).
Tiago Folgosa Granja (844738), David Köhler (147965), Peter Rosenberger (37609), Mariella Schneider (844737), Judith Marlene Roth (844736)   +4 more
core   +1 more source

Evaluation of SEMA7A expression in primary OSCCs.

, 2015
(A, B) Representative sq-IHC results of SEMA7A in primary OSCCs and normal oral tissues. Original magnification, ×200. Scale bars, 50 μm. (C) The status of SEMA7A protein expression in primary OSCCs (n = 150) and normal counterparts based on the sq-IHC ...
Isao Miyamoto (797074), Takane Suzuki (797075), Manabu Iyoda (359431), Yosuke Endo-Sakamoto (359437), Masashi Shiiba (281853), Atsushi Kasamatsu (281849), Hideki Tanzawa (145219), Kengo Saito (593605), Katsuhiro Uzawa (145207), Tomoaki Saito (797073), Katsunori Ogawara (281852)   +10 more
core   +1 more source

Oligogenic Inheritance Underlying Incomplete Penetrance of PROKR2 Mutations in Hypogonadotropic Hypogonadism

Frontiers in Genetics, 2021
The role of the prokineticin 2 pathway in human reproduction, olfactory bulb morphogenesis, and gonadotropin-releasing hormone secretion is well established.
Rahma Mkaouar, Rahma Mkaouar, Lamia Cherif Ben Abdallah, Chokri Naouali, Saida Lahbib, Zinet Turki, Sahar Elouej, Yosra Bouyacoub, Maali Somai, Kenneth Mcelreavey, Anu Bashamboo, Sonia Abdelhak, Olfa Messaoud   +12 more
doaj   +1 more source

Epigenetic‐Based Evidence for Distinct Effects of Age, Sex, and Experience in Developmental Critical Period Learning

Developmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Although much is known about the encoding of experience, how the brain organizes neural circuits capable of learning and memory formation is largely unstudied. Canonical critical periods emerge from a convergence of maturation‐ and experience‐dependent processes.
Grant W. Kunzelman, Alice Batistuzzo, Sarah E. London   +2 more
wiley   +1 more source