Results 101 to 110 of about 16,976 (234)

Role of Robo1 receptor in semaphorin signalling system and cortical interneuron migration

, 2010
En route to the cerebral cortex, interneurons encounter the developing striatum and avoid it. It has been shown that these cells express neuropilin (Nrp) as well as PlexinA receptors, which allow these cells to respond to Sema3A and Sema3F ...
Hernandez-Miranda, L.R.
core  

Semaphorin 3A Levels in Lupus with and without Secondary Antiphospholipid Antibody Syndrome and Renal Involvement

, 2022
© 2021 American Society for Clinical Pathology, 2021. All rights reserved.Objective: The aim of this study is to evaluate semaphorin 3A levels in patients with systemic lupus erythematosus (SLE) with and without renal involvement and secondary ...
Güven, Serdar Can, Apaydln, Hakan, Topçuoǧlu, Canan, Gök, Kevser, Erden, ABDULSAMET, Bayram, Gözde Sevgi Kart, Özdemir, Bahar, Maraş, Yüksel, Bayram, Doǧan, Ateş, Ortaç, Erten, Şükran, Omma, Ahmet, Armaǧan, Berkan, Küçükşahin, Orhan, Karakaş, Özlem   +14 more
core   +1 more source

Tapinarof as a Therapeutic Aryl Hydrocarbon Receptor‐Modulating Agent in the Treatment of Atopic Dermatitis

The Journal of Dermatology, Volume 53, Issue 6, Page 867-879, June 2026.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji, Yoko Fuyuno, Koji Kawamura, Ayako Yumine, Masaki Takemura, Yasutaka Mitamura, Kazuhiko Yamamura, Takeshi Nakahara   +7 more
wiley   +1 more source

Structure of the Semaphorin-3A Receptor Binding Module

, 2003
The semaphorins are a large group of extracellular proteins involved in a variety of processes during development, including neuronal migration and axon guidance.
van Leyen, Klaus, William A. Barton, Claudia Hoemme, Min Lu, Lu, Min, Alexander Antipenko, Püschel, Andreas W., Juha-Pekka Himanen, Kanagalaghatta R. Rajashankar, Nikolov, Dimitar B., Nardi-Dei, Vincenzo, Andreas W. Püschel, Vincenzo Nardi-Dei, Jacob Lesniak, Barton, William A., Klaus van Leyen, Dimitar B. Nikolov, Hoemme, Claudia, Lesniak, Jacob, Antipenko, Alexander, Rajashankar, Kanagalaghatta R., Himanen, Juha-Pekka   +21 more
core   +1 more source

Neuronal guidance signaling in neurodegenerative diseases: Key regulators that function at neuron-glia and neuroimmune interfaces

Neural Regeneration Research
The nervous system processes a vast amount of information, performing computations that underlie perception, cognition, and behavior. During development, neuronal guidance genes, which encode extracellular cues, their receptors, and downstream signal ...
Junichi Yuasa-Kawada, Mariko Kinoshita-Kawada, Masaki Hiramoto, Satoru Yamagishi, Takayasu Mishima, Shin’ichiro Yasunaga, Yoshio Tsuboi, Nobutaka Hattori, Jane Y. Wu   +8 more
doaj   +1 more source

Biochemical bone biomarkers in plasma cell dyscrasias

British Journal of Haematology, Volume 208, Issue 6, Page 1909-1923, June 2026.
Visual abstract depicting that bone turnover markers reflect dynamic alterations in bone remodelling across the spectrum of plasma cell dyscrasias but remain limited by assay variability, biological confounding and incomplete integration with imaging and risk stratification.
Guido Nador, Rohit Vijjhalwar, Muhammad Kassim Javaid, Claire M. Edwards, Karthik Ramasamy   +4 more
wiley   +1 more source

Fragile X mental retardation protein is involved in protein synthesis-dependent collapse of growth cones induced by Semaphorin-3A

Frontiers in Neural Circuits, 2009
Fragile X syndrome, the most frequent form of familial mental retardation, is caused by mutation of the Fmr1 gene. Fmr1 encodes the Fragile X Mental Retardation Protein (FMRP), an mRNA binding protein regulating local, postsynaptic mRNA translation ...
Chanxia Li, Gary j Bassell, Gary j Bassell, Yukio Sasaki   +3 more
doaj   +1 more source

Exploring the Potential of Calebin‐A in Targeting Obesity‐Related Genes and Pathways

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Obesity is a global health crisis affecting millions, associated with metabolic disorders such as type 2 diabetes and cardiovascular disease. Calebin‐A, a bioactive compound derived from Curcuma species, has shown promise in managing obesity and its complications.
Ali Mahmoudi, Ali Saeedi‐Boroujeni, Sercan Karav, Prashant Kesharwani, Amirhossein Sahebkar   +4 more
wiley   +1 more source

Immunohistochemical localization of semaphorin 3A in kidney after different treatments.

, 2013
Immunohistochemical localization of semaphorin 3A was carried out as described in Materials and Methods. Immunostaining for semaphorin 3A is seen in thick ascending limb of the loop of Henle and distal tubular epithelial cells. Scale Bar: 100 µM.
Calpurnia Jayakumar (341127), Catherine D. Krawczeski (385223), Punithavathi Ranganathan (385222), Ganesan Ramesh (341131), Prasad Devarajan (38870), Stephen Looney (237505)   +5 more
core   +1 more source

The Role of Immune Semaphorins in Sepsis—A Prospective Cohort Study

Microorganisms
In sepsis, a balanced pro-inflammatory and anti-inflammatory response results in the bacterial clearance and resolution of inflammation, promoting clinical recovery and survival.
Branimir Gjurasin, Lara Samadan Markovic, Leona Radmanic Matotek, Neven Papic   +3 more
doaj   +1 more source