Results 91 to 100 of about 16,976 (234)
eLife, 2017 The ellipsoid body (EB) in the Drosophila brain is a central complex (CX) substructure that harbors circumferentially laminated ring (R) neuron axons and mediates multifaceted sensory integration and motor coordination functions.
Xiaojun Xie +5 more
doaj +1 more source
Global Challenges, Volume 10, Issue 6, June 2026.Low‐dose hydrogen peroxide priming shapes Manila clam responses to simulated marine heatwaves, which showed faster burrowing behavior, limited transcriptional disruption, and reduced opportunistic microbiota. A long‐term field trial confirms no detectable adverse effects, supporting redox‐based chemical priming as a feasible resilience strategy in ...
Chiara Mascitelli +14 more
wiley +1 more source
Movement Disorders, Volume 41, Issue 6, Page 1492-1501, June 2026.Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar +15 more
wiley +1 more source
Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation
, 2012 International audienceVE-cadherin-mediated cell-cell junction weakening increases paracellular permeability in response to both angiogenic and inflammatory stimuli.
Dubois, Sonia +10 more
core +1 more source
Semaphorin 3F and Netrin-1: The Novel Function as a Regulator of Tumor Microenvironment
Frontiers in Physiology, 2018 Axon guidance molecules play an important role in regulating proper neuronal networking during neuronal development. They also have non-neuronal properties, which include angiogenesis, inflammation, and tumor development. Semaphorin 3F (SEMA3F), a member
Hironao Nakayama +5 more
doaj +1 more source
Semaphorin Receptor Function in Hedgehog Signal Transduction [PDF]
, 2018 Hedgehog signaling is a conserved cell-cell communication pathway that plays essential and diverse roles during embryonic development and adult tissue homeostasis. Many cell surface-associated molecules critically regulate the Hedgehog signaling pathway,
Pinskey, Justine
core
Semaphorin-7A blocks α-SMA and periostin production in HLF.
, 2017 HLF derived from non-fibrotic lungs were treated with the indicated siRNAs for 24 h. HLF were subsequently starved in BSA for 24 h before either adding TGF-ß (1 ng/ml) or left in BSA for 20 h.
Elizabeth A. Kelly (429798) +6 more
core +1 more source
Immunohistochemical distribution of Plexin A4 in the adult rat central nervous system
Frontiers in Neuroanatomy, 2010 PlexinA4 is the latest member to be identified of the plexin A subfamily, critical transducers of class 3 semaphorin signaling as co-receptors to neuropilins 1 and 2.
Claire-Anne Gutekunst +2 more
doaj +1 more source
From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies
Portal Hypertension &Cirrhosis, Volume 5, Issue 2, Page 170-188, June 2026.This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu +5 more
wiley +1 more source