Results 41 to 50 of about 7,206 (213)
Plexin-B2 controls the timing of differentiation and the motility of cerebellar granule neurons
eLife, 2021 Plexin-B2 deletion leads to aberrant lamination of cerebellar granule neurons (CGNs) and Purkinje cells. Although in the cerebellum Plexin-B2 is only expressed by proliferating CGN precursors in the outer external granule layer (oEGL), its function in ...
Eljo Van Battum +5 more
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Role of Semaphorins in Ischemic Stroke
Frontiers in Molecular Neuroscience, 2022 Ischemic stroke is one of the major causes of neurological morbidity and mortality in the world. Although the management of ischemic stroke has been improved significantly, it still imposes a huge burden on the health and property.
Huaping Du, Yuan Xu, Li Zhu, Li Zhu
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Semaphorins guide PerPlexeD endothelial cells
, 2004 Abrogation of the endothelial cell-specific semaphorin receptor PlexinD1 in zebrafish and mouse reveals semaphorin functions selectively affecting the cardiovascular system.
Deutsch, U, Deutsch, Urban
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Class IV semaphorins in disease pathogenesis [PDF]
This is the peer reviewed version of the following article: Nojima, S. Class IV semaphorins in disease pathogenesis. Pathol. Int. 2022; 72: 471– 487, which has been published in final form at https://doi.org/10.1111/pin.13270.
Nojima, Satoshi
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The role of semaphorins in allergic diseases
Allergology InternationalSemaphorins were originally identified as guidance molecules in neural development. However, accumulating evidence indicates that ‘immune semaphorins’ are critically involved in regulating immune cell activation, differentiation, mobility and migration ...
Maiko Naito, Atsushi Kumanogoh
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Semaphorins and their Signaling Mechanisms [PDF]
, 2016 Semaphorins are extracellular signaling proteins that are essential for the development and maintenance of many organs and tissues. The more than 20-member semaphorin protein family includes secreted, transmembrane and cell surface-attached proteins with diverse structures, each characterized by a single cysteine-rich extracellular sema domain, the ...
Laura Taylor, Alto, Jonathan R, Terman
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Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
BMEMat, EarlyView.This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
Acta Medica BulgaricaSemaphorins, initially identified as phylogenetically conserved axon guidance molecules, comprise an extracellular signaling protein family involved in various biological events that regulate the development, tissue homeostasis and cancer progression of ...
Popov Ts.
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WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy
Epilepsia, EarlyView.Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara +7 more
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Semaphorins and Plexins in Kidney Disease
, 2016 Semaphorins are soluble or membrane-bound cues, which control multiple aspects of cell-cell communication, differentiation, morphology and function. Most of their effects are mediated by a family of transmembrane receptors called plexins. Semaphorins and
Xia, J., Xia , J., Worzfeld, T.
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