Results 191 to 200 of about 51,520 (299)

A spatiotemporal atlas of senescence-associated secretory phenotype in fracture healing: stage-dependent mechanisms and therapeutic windows. [PDF]

Inflamm Regen
Chen B, Li G, Fang Q, Ding P, Gao Y.
europepmc   +1 more source

The aged extracellular matrix and the profibrotic role of senescence-associated secretory phenotype

, 2023
Yohannes A. Mebratu, Sourabh Soni, Lorena Rosas, Mauricio Rojas, Jeffrey C. Horowitz, Richard Seonghun Nho   +5 more
openalex   +2 more sources

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Analysis of molecular subtypes and prognostic signature of senescence-associated secretory phenotype in pancreatic cancer. [PDF]

PeerJ
Kuang Y, Jia M, Zhu Y, Xiang Z.
europepmc   +1 more source

COPD-derived fibroblasts secrete higher levels of senescence associated secretory phenotype (SASP) proteins

, 2020
Roy R. Woldhuis, Irene H. Heijink, Maarten van den Berge, Wim Timens, Brian G. Oliver, Maaike de Vries, Corry‐Anke Brandsma   +6 more
openalex   +2 more sources

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

The controversial role of senescence-associated secretory phenotype (SASP) in cancer therapy. [PDF]

Mol Cancer
Cao L, Li K, Li Q, Tong Q, Wang Y, Huang L.   +5 more
europepmc   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

The Impact of Senescence-Associated Secretory Phenotype (SASP) on Head and Neck Cancers: From Biology to Therapy. [PDF]

Cancers (Basel)
Alam MT, Mansoor MAM, Ashiqueali SA, Golusinski P, Golusinska-Kardach E, Strzelczyk JK, Rubis B, Golusinski W, Masternak MM.   +8 more
europepmc   +1 more source

Supplementary Fig. S3 from Paracrine Interaction of Cancer Stem Cell Populations Is Regulated by the Senescence-Associated Secretory Phenotype (SASP)

, 2023
Angelica M. Lagunas, Marybeth Francis, Nisha B. Maniar, Gergana Nikolova, Jianchun Wu, David L. Crowe   +5 more
openalex   +1 more source