Results 221 to 230 of about 51,520 (299)

The Application Value of Transvaginal Three‐Dimensional Ultrasonography in the Diagnosis of Adenomyosis of the Uterus

Journal of Clinical Ultrasound, EarlyView.
In this study, 3D‐TVS measurements of the uterine junction zone (JZ) in 120 patients showed that a JZmax threshold of ≥ 0.45 cm yielded 77% sensitivity and 89% specificity for adenomyosis diagnosis. Notably, JZ thickness varies minimally with age, demonstrating its stability and excellent diagnostic performance.
Mengyu Li, Zhen Zong, Xiaoman Wang, Hebin Zhang   +3 more
wiley   +1 more source

Immunoregulatory mechanisms in the aging microenvironment: Targeting the senescence-associated secretory phenotype for cancer immunotherapy. [PDF]

Acta Pharm Sin B
Wang H, Yu Y, Li R, Zhang H, Chen ZS, Sun C, Zhuang J.   +6 more
europepmc   +1 more source

Dasatinib and quercetin prevent alveolar bone loss in aged mice

Journal of Periodontology, EarlyView.
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli, Renata M. Moraes, Yuri C. Santos, Jaqueline L. Ribeiro, Maíra T. Garcia, Renata F. Prado, Florent Elefteriou, Ana Lia Anbinder   +7 more
wiley   +1 more source

Integrative Transcriptomic and Machine Learning Analysis Identifies Key Senescence-Associated Secretory Phenotype Genes Associated With Immune Dysregulation in Periodontitis. [PDF]

Hum Mutat
Zeng J, Huang J, He J, Tan J, Duan M, Song Y, Yang L.   +6 more
europepmc   +1 more source

The role of high mobility group Box 1 (HMGB1) in the formation of senescence-associated secretory phenotype and age-related changes (Review)

Ігор Сенюк, В. М. Кравченко, Л. В. Галузінська, Oleksandr Honcharov, Nodar Sulashvili, Олена Валентинівна Щербак   +5 more
openalex   +2 more sources

Aging and periodontitis increase brain dissemination of oral bacteria

Journal of Periodontology, EarlyView.
Abstract Background The microbiome is a dynamic system that changes throughout life. Studies have revealed the relationship between periodontal disease and the oral microbiota; however, the impact of periodontal disease on the expression of senescence markers and on the inflammaging of the oral and systemic microbiome remains unclear.
Ozge Unlu, Tsute Chen, Nil Yakar, Zeliha Guney, Bruce Paster, Isabel Carreras, Alpaslan Dedeoglu, Alpdogan Kantarci   +7 more
wiley   +1 more source

Senescent bone marrow mesenchymal stem cells exacerbate subchondral bone sclerosis and osteoarthritis via the senescence-associated secretory phenotype. [PDF]

Stem Cell Res Ther
Yang D, Xu X, Xu K, Yang M, Hao Y, Aihaiti Y, Li E, Yan Y, Lu C, Xu P.   +9 more
europepmc   +1 more source

Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang, Hai Wang, Yong‐Zheng Zhang, Yan‐Yan Chen, Xin‐Xin Xing, Yi‐Cheng Ding   +5 more
wiley   +1 more source

Senescence-associated secretory phenotype in lung cancer: remodeling the tumor microenvironment for metastasis and immune suppression. [PDF]

Front Oncol
Chen C, Chen J, Zhang Y, Zhang Q, Shi H.
europepmc   +1 more source

Table S1 from Oncolytic HSV-1–Mediated JAG1 Blockade Induces Glioma Senescence-Associated Secretory Phenotype to Increase Macrophage Activation and Cetuximab-Mediated Senolysis

Kimberly Rivera-Caraballo, Tae Jin Lee, Arnoneel Sinha, Marco Orecchioni, Rafał Pacholczyk, Karina Vázquez-Arreguín, Shilpa Sharma, Kimya Jones, Kailash Vemuri, Upasana Sahu, Sara A. Murphy, Bangxing Hong, Ravindra Kolhe, Ashok Sharma, Balveen Kaur   +14 more
openalex   +1 more source