Results 31 to 40 of about 7,601,900 (287)
Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain. [PDF]
, 2013 Bispecific antibodies are considered as a promising class of future biotherapeutic molecules. They comprise binding specificities for two different antigens, which may provide additive or synergistic modes of action.
Duerr, Harald +29 more
core +2 more sources
Ricin Detection Using Phage Displayed Single Domain Antibodies
Sensors, 2009 Phage-displayed single domain antibodies (sdAb) were compared to monomeric solubly expressed sdAb and llama polyclonal antibodies for the detection of ricin. SdAb are comprised of the variable domain derived from camelid heavy chain only antibodies (HcAb)
Ellen R. Goldman +5 more
doaj +1 more source
Nature Communications, 2020 Here, using a humanized phage display library with recombinant SARS- CoV-2 receptor binding domain (RBD) proteins, the authors identify a number of single domain antibodies (sdAbs) that neutralize SARS-CoV-2 in vitro by inhibiting the interaction of the ...
Xiaojing Chi +9 more
doaj +1 more source
Progress of Single-domain Antibodies in Molecular Imaging of Tumors
Zhongliu Fangzhi Yanjiu, 2019 A single-domain antibody (sdAb) is the variable region extracted from antibodies with only heavy chains found in camelid serum. Single-domain antibodies have the characteristics of easy expression, good solubility, great stability and weak immunogenicity.
ZHANG Meixin +5 more
doaj +1 more source
Scientific Reports, 2021 The high binding affinities and specificities of antibodies have led to their use as drugs and biosensors. Single-domain VHH antibodies exhibit high specificity and affinity but have higher stability and solubility than conventional antibodies as they ...
Emina Ikeuchi +4 more
doaj +1 more source
Frequency-domain precoding for single carrier frequency-division multiple access [PDF]
, 2009 At present there is considerable interest in the use of single carrier frequency-division multiple access. This interest is justified by the inherent single carrier structure of the SC-FDMA scheme, which is more robust against phase noise and has a lower
Nix, AR, Noune, MB
core +1 more source
Application of single-domain antibodies ("nanobodies") to laboratory diagnosis
, 2021 Antibodies have proven to be central in the development of diagnostic methods over decades, moving from polyclonal antibodies to the milestone development of monoclonal antibodies.
Pillay, Tahir S., Muyldermans, Serge
core +1 more source
, 2023 Data includes supplementary information for the research article "Physicochemical differences between camelid single-domain antibodies and mammalian antibodies".
Eskier, D (via Mendeley Data)
core +2 more sources
Single-Domain Antibodies: Biology, Engineering and Emerging Applications
, 2018 Single-domain antibodies (sdAbs) represent the minimal antigen binding-competent form of the immunoglobulin domain and have unique properties and applications.
Henry, Kevin A. +3 more
core +1 more source
Liver-Targeting of Interferon-Alpha with Tissue-Specific Domain Antibodies [PDF]
, 2013 PMCID: PMC3581439This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Ovecka, M +47 more
core +2 more sources