Results 51 to 60 of about 217,308 (243)
Optimized background suppression in near field lidar telescopes [PDF]
, 2003 It is shown that a tilted slit in the focal plane of the lidar telescope limits the telescopes field of view efficiently and suppresses the background in the lidar signal by up to an order of magnitude better than a circular ...
Freudenthaler, Volker
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Signaling at the Slit Diaphragm [PDF]
Journal of the American Society of Nephrology, 2004 Diseases of the glomerular filter of the kidney are a leading cause of end-stage renal failure. Recent studies have emphasized the critical role of the slit diaphragm of podocytes for the size-selective filtration barrier of the kidney and revealed novel aspects of the mechanisms that lead ...
openaire +3 more sources
The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm. [PDF]
, 2008 The nephron is the basic structural and functional unit of the vertebrate kidney. It is composed of a glomerulus, the site of ultrafiltration, and a renal tubule, along which the filtrate is modified. Although widely regarded as a vertebrate adaptation, '
Bader, Augustinus +16 more
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Slit Diaphragm Protein Neph1 and Its Signaling [PDF]
Journal of Biological Chemistry, 2014 Podocytes are specialized epithelial cells that are critical components of the glomerular filtration barrier, and their dysfunction leads to proteinuria and renal failure. Therefore, preserving podocyte function is therapeutically significant. In this study, we identified Neph1 signaling as a therapeutic target that upon inhibition prevented podocyte ...
Ehtesham Arif +6 more
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The Kantian Framework of Complementarity [PDF]
, 2010 A growing number of commentators have, in recent years, noted the important affinities in the views of Immanuel Kant and Niels Bohr. While these commentators are correct, the picture they present of the connections between Bohr and Kant is painted in ...
Allison +37 more
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Molecular Evolution of Podocyte Slit-diaphragm Proteins [PDF]
, 2020 AbstractVertebrates kidneys contribute to the homeostasis by regulating electrolyte, acid-base balance, and prevent protein loss into the urine. Glomerular podocytes constitute blood-urine barrier and podocyte slit-diaphragm, a modified tight junction contributes to the glomerular permselectivity. Nephrin, podocin, CD2AP, and TRPC6 are considered to be
NSK Mulukala +3 more
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A new outlook towards kidney injuries [PDF]
, 2012 Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Abhijeet Satwekar, Mahesh Satwekar
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The Glomerular Slit Diaphragm Is a Modified Adherens Junction [PDF]
Journal of the American Society of Nephrology, 2000 Abstract. The glomerular slit diaphragm between podocyte foot processes shares typical morphologic features with an adherens junction. Differentiated cultured podocytes form cellular structures comparable to filtration slits in vivo. At those sites, zonula occludens-1 (ZO-1) was coexpressed with P-cadherin as well as with α-, β-
Jochen, Reiser +3 more
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Nephrin-Binding Ephrin-B1 at the Slit Diaphragm Controls Podocyte Function through the JNK Pathway.
J Am Soc Nephrol, 2018 Fukusumi Y +6 more
europepmc +2 more sources
Frontiers in Cell and Developmental Biology, 2023 Introduction: The unique architecture of glomerular podocytes is integral to kidney filtration. Interdigitating foot processes extend from the podocyte cell body, wrap around fenestrated capillaries, and form specialized junctional complexes termed slit ...
Gary F. Gerlach +4 more
doaj +1 more source