Results 51 to 60 of about 7,412 (180)
Ephrin-B1 localizes at the slit diaphragm of the glomerular podocyte [PDF]
Kidney International, 2007 Ephs and ephrins are a family of membrane-bound proteins that function as receptor-ligand pairs. Members of the Eph-ephrin-B family have recently been reported to regulate the paracellular permeability of epithelial cells. In this study, we analyzed the expression and the function of ephrin-B1 in glomeruli.
Hashimoto, T. +7 more
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Genetic Basis of Steroid Resistant Nephrotic Syndrome [PDF]
Childhood Kidney Diseases, 2019 Steroid-resistant nephrotic syndrome (SRNS) has long been a challenge for clinicians due to its poor responsiveness to immunosuppressants, and rapid progression to end-stage renal disease.
Eujin Park
doaj +1 more source
Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis. [PDF]
PLoS ONE, 2010 BACKGROUND: Microalbuminuria is an early lesion during the development of diabetic nephropathy. The loss of high molecular weight proteins in the urine is usually associated with decreased expression of slit diaphragm proteins.
Irini Tossidou +9 more
doaj +1 more source
Acta Cirúrgica Brasileira, 2006 PURPOSE: To determine the number of podocyte, slit diaphragms, slit diaphragm extensions and GBM thickness in diabetic nephropathy. METHODS: Sixty "Rattus Wistar"of both sexes weighing 200-300g were divided in two experimental groups: normal group 10 ...
Mauro Masson Lerco +4 more
doaj +1 more source
Nephrin is specifically located at the slit diaphragm of glomerular podocytes [PDF]
Proceedings of the National Academy of Sciences, 1999 We describe here the size and location of nephrin, the first protein to be identified at the glomerular podocyte slit diaphragm. In Western blots, nephrin antibodies generated against the two terminal extracellular Ig domains of recombinant human nephrin recognized a 180-kDa protein in lysates of human glomeruli and a 150-kDa protein in transfected COS-
V, Ruotsalainen +7 more
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The structural and functional organization of the podocyte filtration slits is regulated by Tjp1/ZO-1. [PDF]
PLoS ONE, 2014 Blood filtration in the kidney glomerulus is essential for physiological homeostasis. The filtration apparatus of the kidney glomerulus is composed of three distinct components: the fenestrated endothelial cells, the glomerular basement membrane, and ...
Masahiko Itoh +6 more
doaj +1 more source
POROUS SUBSTRUCTURE OF THE GLOMERULAR SLIT DIAPHRAGM IN THE RAT AND MOUSE [PDF]
The Journal of Cell Biology, 1974 The highly ordered, isoporous substructure of the glomerular slit diaphragm was revealed in rat and mouse kidneys fixed by perfusion with tannic acid and glutaraldehyde. The slit diaphragm was similar in both animal species and appeared as a continuous junctional band, 300–450 Å wide, consistently present within all slits formed by the epithelial foot
R, Rodewald, M J, Karnovsky
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Modular, Textile‐Based Soft Robotic Grippers for Agricultural Produce Handling
Advanced Robotics Research, EarlyView.This article introduces textile‐based pneumatic grippers that transform simple textiles into robust bending actuators. Detailed experiments uncover how cut geometry and fabric selection shape performance. Successful handling of fragile agricultural items showcases the potential of textile robotics for safe, scalable automation in food processing and ...
Zeyu Hou +4 more
wiley +1 more source
Recurrent Focal Segmental Glomerulosclerosis: A Discrete Clinical Entity
International Journal of Nephrology, 2012 Focal segmental glomerulosclerosis refers to a set of particular histopathologic lesions in which steroid-resistant podocyte injury leads to patchy adhesions between the glomerular tuft and Bowman's capsule, followed by progressive glomerulosclerosis and
Elena Torban +2 more
doaj +1 more source
Lipid–Protein Interactions along the Slit Diaphragm of Podocytes [PDF]
Journal of the American Society of Nephrology, 2009 Podocytes are visceral epithelial cells supporting the function of the glomerular filter. Interdigitating foot processes of podocytes enwrap the glomerular capillaries and are connected by a highly specialized cell junction, the slit diaphragm. Signal transduction at the slit diaphragm is essential for the proper function of the kidney filtration ...
Bernhard, Schermer, Thomas, Benzing
openaire +2 more sources