Results 21 to 30 of about 5,853,742 (252)
Heliyon, 2023 Objective: Colorectal cancer remains a significant challenge with high mortality rates. The aim of this study was to investigate the effect of targeting the microRNA-148a/WNT10b axis with the long non-coding RNA LINC00261 on the proliferation and ...
Juanli Xi +4 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2023 Small interfering RNA (siRNA)-mediated mRNA degradation approach have imparted its eminence against several difficult-to-treat genetic disorders and other allied diseases.
Rushikesh Fopase +6 more
doaj +1 more source
Binding of small interfering RNA molecules is crucial for RNA interference suppressor activity of rice hoja blanca virus NS3 in plants [PDF]
, 2009 The NS3 protein of rice hoja blanca tenuivirus represents a viral suppressor of RNAi that sequesters small interfering (si)RNAs in vitro. To determine whether this siRNA binding property is the critical determinant for the suppressor activity of NS3, an ...
Kaaij, L. +5 more
core +1 more source
A small RNA response at DNA ends in Drosophila [PDF]
, 2012 Small RNAs have been implicated in numerous cellular processes, including effects on chromatin structure and the repression of transposons. We describe the generation of a small RNA response at DNA ends in Drosophila that is analogous to the recently ...
Förstemann, Klaus +2 more
core +1 more source
Novel Cell type-specific aptamer-siRNA delivery system for HIV-1 therapy [PDF]
, 2007 The successful use of small interfering RNAs (siRNAs) for therapeutic purposes requires safe and efficient delivery to specific cells and tissues. Here we demonstrate cell type-specific delivery of anti-HIV siRNAs via fusion to an anti-gp120 aptamer. The
Haitang Li +4 more
core +1 more source
Nucleolar dominance and DNA methylation directed by small interfering RNA [PDF]
, 2008 In the December 5th issue of Molecular Cell, Preuss et al. (2008) demonstrated a link between small interfering RNA (siRNA)-directed de novo DNA methylation and rDNA silencing in nucleolar ...
Finigan, P., Martienssen, R. A.
core +1 more source
Small Farm Quarterly - Fall 2011 [PDF]
, 2011 Small Farm Quarterly is for farmers and farm families — including spouses and children - who value the quality of life that smaller farms provide.CONTENTS: SMALL FARM PROGRAM UPDATE -Cornell Small Farms Program Update, Page 3; COMMUNITY AND WORLD -Boat-
Cornell Small Farms Program
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Small Interfering RNA in Colorectal Cancer Liver Metastasis Therapy
Technology in Cancer Research & Treatment, 2022 Colorectal cancer (CRC) is associated with numerous genetic disorders and cellular abnormalities, and liver metastasis is a common health concern in patients with CRC.
Junlin Xie MM, Shubin Wang MD
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Silencing small interfering RNA sequences.
, 2015 Silencing small interfering RNA sequences.
Michael Anthony Ruiz (726055) +2 more
core +1 more source
Small interfering RNA against BCR-ABL transcripts sensitize mutated T315I cells to nilotinib
Haematologica, 2010 Background Selective inhibition of the BCR-ABL tyrosine kinase by RNA interference has been demonstrated in leukemic cells. We, therefore, evaluated specific BCR-ABL small interfering RNA silencing in BCR-ABL-positive cell lines, including those ...
Michael Koldehoff +3 more
doaj +1 more source