Results 31 to 40 of about 5,853,742 (252)

Short Hairpin RNAs for Strand-Specific Small Interfering RNA Production

Frontiers in Bioengineering and Biotechnology, 2020
RNA interference (RNAi) is an effective mechanism for inhibiting gene expression at the post-transcriptional level. Expression of a messenger RNA (mRNA) can be inhibited by a ∼22-nucleotide (nt) small interfering (si)RNA with the corresponding reverse ...
Peike Sheng, Peike Sheng, Krystal A. Flood, Krystal A. Flood, Mingyi Xie, Mingyi Xie, Mingyi Xie   +6 more
doaj   +1 more source

cd26 Knockdown Negatively Affects Porcine Parthenogenetic Preimplantation Embryo Development

Animals, 2022
cd26 is ubiquitously distributed in the body, particularly in the endothelial and epithelial cells, with the highest expression in the kidney, liver, and small intestine. In humans, cd26 serves as a marker for the embryo implantation phase.
In-Sul Hwang, Joohyun Shim, Keon Bong Oh, Haesun Lee, Mi-Ryung Park   +4 more
doaj   +1 more source

INTEGRATIVE COMPUTER ANALYSIS OF ANTISENSE TRANSCRIPTS AND miRNA TARGETS IN PLANT GENOMES [PDF]

Journal of Stress Physiology & Biochemistry, 2012
Non-coding RNA, including small interfering RNAs (siRNAs), are important components of gene expression in eukaryotes, forming a regulatory network. miRNAs are expressed through nucleolytic maturation of hairpin precursors transcribed by RNA Polymerase II
Orlov Y.L., O. Dobrovolskaya, C.H. Yuan, D.A. Afonnikov, Y. Zhu, M. Chen   +5 more
doaj  

Sequences of small interfering RNA (siRNA).

, 2013
Sequences of small interfering RNA (siRNA).
Ming-Qing Li (313711), Li-Rong Xue (313710), Yan-Li Hou (313709), Mei-Rong Du (305223), Da-Jin Li (305225), Hong-Bo Zhao (313707), Chuan-Ling Tang (313708)   +6 more
core   +1 more source

Antitumor effects of small interfering RNAs

Медицинская иммунология
The aim of our work was to summarize the existing results in anticancer therapy with small interfering RNAs (siRNAs), as well as to highlight the role of siRNA as a remodulator of the immune response in oncological diseases.
E. A. Pashkov, A. A. Murzina, I. B. Semenova, M. N. Shatokhin, O. A. Svitich, V. V. Zverev   +5 more
doaj   +1 more source

EGCG‐LYS Fibrils‐Mediated CircMAP2K2 Silencing Decreases the Proliferation and Metastasis Ability of Gastric Cancer Cells in Vitro and in Vivo

Advanced Science, 2023
Aberrant expression of circular RNAs (circRNAs) has been reported to play an important biological regulatory role in gastric cancer (GC). For the purpose of silencing cancer‐related genes, a new approach for cancer treatment using nanocarriers to deliver
Jiaqi Dong, Zhousan Zheng, Mi Zhou, Yunfei Wang, Jiajie Chen, Junjie Cen, Tiefeng Cao, Taowei Yang, Yi Xu, Guannan Shu, Xuanxuan Lu, Yanping Liang   +11 more
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Small interfering (siRNA) sequences used in siRNA based experiments.

, 2015
Small interfering (siRNA) sequences used in siRNA based experiments.
Justin Jang Hann Chu (128668), Regina Ching Hua Lee (280378)   +1 more
core   +1 more source

Development of therapeutic-grade small interfering RNAs by chemical engineering

Frontiers in Genetics, 2012
Recent successes in clinical trials have provided important proof of concept that small interfering RNAs indeed constitute a new promising class of therapeutics.
Jesper Bertram Bramsen, Jørgen eKjems
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source