Results 51 to 60 of about 1,687,750 (295)

Solid-State Spectroscopic Investigation of Molecular Interactions between Clofazimine and Hypromellose Phthalate in Amorphous Solid Dispersions

, 2016
It has been technically challenging to specify the detailed molecular interactions and binding motif between drugs and polymeric inhibitors in the solid state.
Anthony Leone (1801816), Stephen R. Byrn (1386339), Tonglei Li (1574197), Haichen Nie (1415980), Patrick J. Marsac (811779), Mingtao Zhang (832481), Yang Song (1235364), Lynne S. Taylor (1349709), Yongchao Su (1317195)   +8 more
core   +1 more source

Parents of Youth With Cancer Report on Their Psychosocial Care: iSTEPPP Survey Finds Alignment and Gaps With Standards

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau, Kimberly Buff, Michele A. Scialla, Kimberly S. Canter, Lori Wiener, Victoria Sardi‐Brown, Julia B. Tager, Kamyar Arasteh, Anne E. Kazak   +8 more
wiley   +1 more source

Applying Supercritical Fluid Technology to Prepare Ibuprofen Solid Dispersions with Improved Oral Bioavailability

Pharmaceutics, 2019
In this study, supercritical fluid (SCF) technology was applied to prepare reliable solid dispersions of pharmaceutical compounds with limited bioavailability using ibuprofen (IBU) as a model compound.
Fei Han, Wei Zhang, Ying Wang, Ziyue Xi, Lu Chen, Sanming Li, Lu Xu   +6 more
doaj   +1 more source

Design and Characterization of Phosphatidylcholine-Based Solid Dispersions of Aprepitant for Enhanced Solubility and Dissolution

Pharmaceutics, 2020
This study aimed to improve the solubility and dissolution of aprepitant, a drug with poor aqueous solubility, using a phosphatidylcholine (PC)-based solid dispersion system.
Sooho Yeo, Jieun An, Changhee Park, Dohyun Kim, Jaehwi Lee   +4 more
doaj   +1 more source

Characterization of olanzapine-solid dispersions.

Iranian journal of pharmaceutical research : IJPR, 2011
To enhance the aqueous solubility of olanzapine by using the Solid dispersion technique. Solid dispersions of olanzapine were prepared by the dispersion method using using PGS and SSG as carriers. Drug-carrier ratios such as 1 : 1, 1 : 2, 1 : 4, 1 : 6, 1: 8 and 1 : 10 were tried for optimization.
Krishnamoorthy, Venkateskumar, Nagalingam, Arunkumar, Ranjan Prasad, Verma Priya, Parameshwaran, Siva, George, Neema, Kaliyan, Punitha   +5 more
openaire   +2 more sources

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

Solid dispersions: formulation, characterisation, permeability and genomic evaluation [PDF]

Poor water solubility is characterised by low dissolution rate and consequently reduced bioavailability. Formulation of solid dispersion of the drug has attracted considerable interest as a means of improving dissolution process of a range of poorly ...
Khan, Muhammad
core   +7 more sources

PREPARATION AND EVALUATION OF DOLUTEGRAVIR SOLID DISPERSIONS [PDF]

, 2021
Objective: The current work mainly focuses on solubility enhancement of dolutegravir which is a BCS (Biopharmaceutical Classification System) class-II drug using various excipients.
MUPPARAJU, SUNDEEP, SURYADEVARA, VIDYADHARA, DOPPALAPUDI, SANDEEP   +2 more
core   +1 more source

Screening of Ketoprofen-Poloxamer and Ketoprofen-Eudragit solid dispersions for improved physicochemical characteristics and dissolution profile

Brazilian Journal of Pharmaceutical Sciences, 2020
The aim of the present study was to enhance the dissolution rate of an NSAID drug Ketoprofen by formulating it into solid dispersions with water soluble carrier Poloxamer 188 and Eudragit S 100. The solid dispersions of Ketoprofen with Poloxamer 188 were
Ravi Yashwant Savardekar, Amol Shantinath Sherikar   +1 more
doaj   +1 more source

Amorphous Solid Dispersions: Role of the Polymer and Its Importance in Physical Stability and In Vitro Performance

Pharmaceutics, 2022
Amorphous solid dispersions stabilized by one or more polymer(s) have been widely used for delivering amorphous drugs with poor water solubilities, and they have gained great market success.
Qin Shi, Haibiao Chen, Yanan Wang, Ruoxun Wang, Jia Xu, Chen Zhang   +5 more
doaj   +1 more source