Results 21 to 30 of about 24,357,552 (149)
Albendazolum (ABZ) is a BCS class II drug. It has challenging biopharmaceutical properties, which include poor solubility and dissolution rate. These properties have laid the ground for developing a supersaturated self-nanoemulsifying drug delivery ...
Hani Alothaid +6 more
doaj +1 more source
Aprepitant (APR) belongs to Class II of the Biopharmaceutical Classification System (BCS) because of its low aqueous solubility. The objective of the current work is to develop self-nanoemulsifying drug delivery systems (SNEDDS) of APR to enhance its ...
Hakan Nazlı +2 more
doaj +1 more source
Development of black cumin seed oil (Nigella sativa L.) SNEDDS into solid-SNEDDS and its characterization [PDF]
Black cumin seed oil (MBJH) (Nigella sativa L.) is a well-known herb with pharmacology activities such as anticancer and anti-thrombocytopenia. The limitation of MBJH has poor absorption when using oral dosage form.
Rodhia Ulfa, Dwi Utami, Iis Wahyuningsih
doaj +1 more source
Low-frequency Raman spectroscopy (LFRS) is a valuable tool to detect the solid state of amorphous and crystalline drugs in solid dosage forms and the transformation of drugs between different polymorphic forms.
Malinda Salim +5 more
doaj +1 more source
Background and purpose: Doxazosin mesylate (DOX) is an antihypertensive drug that possesses poor water solubility and, hence, poor release properties.
Al Zahraa G. Al Ashmawy +4 more
doaj +1 more source
Development of self-nanoemulsifying tablet (SNET) for bioavailability enhancement of sertraline
The purpose of the study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form. Self-nanoemulsifying drug delivery system (SNEDDS) was prepared to enhance the solubility and thus oral ...
Mohammad Akhlaquer Rahman +1 more
doaj +1 more source
Background: Curcumin and Thymoquinone are very well-known phytochemicals for their potent anti-inflammatory and anticancer properties. The major challenges for curcumin is its poor aqueous solubility and erratic oral bioavailability.
Majed Alwadei +2 more
doaj +1 more source
Low aqueous solubility and poor oral bioavailability are limiting factors in the oral delivery of voxelotor, an antisickling agent. To overcome these limitations, a voxelotor self-nanoemulsifying drug delivery system was developed.
Mbinze, Jérémie K +13 more
core +1 more source
Formulation and in vitro evaluation of self-nanoemulsifying liquisolid tablets of furosemide
Self-nanoemulsifying drug delivery systems (SNEDDS) were used to enhance the dissolution rate of furosemide as a model for class IV drugs and the system was solidified into liquisolid tablets.
Lena Dalal +2 more
doaj +1 more source
Drug-excipient-shell interactions using thermoplastic starch-based capsules for oral lipid-based drug delivery [PDF]
Worldwide, gelatin has been used in the rotary die process as a shell-forming material of soft capsules due to its unique physicochemical properties.
Misic, Zdravka
core +1 more source

