Results 41 to 50 of about 24,357,552 (149)

Propolis‐Based Hybrid Nanoflowers as Multifunctional Nanozymes: Structural Integration of Polyphenols for Enhanced Catalytic and Antioxidant Activity

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
ABSTRACT Propolis is a polyphenol‐rich natural resin with well‐documented antioxidant activity; however, its practical application is restricted by poor aqueous solubility and limited stability. Herein, propolis‐based organic–inorganic hybrid nanoflowers (Prp‐Nfs) were synthesized by integrating a propolis extract into a Cu3(PO4)2·3H2O matrix under ...
Cevahir Altinkaynak, Fatih Kirmizikar
wiley   +1 more source

SOLID SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) DEVOLOPMENT, APPLICATIONS AND FUTURE PERSPECTIVE: A REVIEW

, 2017
Developments in recent drug discovery programs, yields a large proportion of novel pharmacologically active molecules that are lipophilic and poorly soluble ,which is a major challenge for pharmaceutical researchers to enhance the oral bioavailability of
Febi S Kuruvila*, Flowerlet Mathew ,S Kuppuswamy
core   +1 more source

Lavender‐Oil Fusidic Acid Nanoemulgel: A Novel Strategy Against Fusidic Acid‐Resistant Staphylococcus aureus

Nano Select, Volume 7, Issue 3, March 2026.
A topical Fusidic acid nanoemulgel is developed using a self‐nanoemulsifying system and optimized via ternary phase diagrams. Lavender oil enables efficient drug solubilization, while Carbopol 940 hydrogels provide favorable rheological behavior.
Ahmad M. Eid, Hani Naseef, Sana Abu Omar, Asmaa Hawawerh, Yasmeen Abu Baker, Jude Salameh, Israr Sabri, Abdulraziq Zarour   +7 more
wiley   +1 more source

Preparation, characterization, and in vivo evaluation of a self-nanoemulsifying drug delivery system (SNEDDS) loaded with morin-phospholipid complex [PDF]

, 2011
Background: As a poorly water-soluble drug, the oral application of morin is limited by its low oral bioavailability. In this study, a new self-nanoemulsifying drug delivery system (SNEDDS), based on the phospholipid complex technique, was developed to ...
Zhang, Jinjie, Zhang, Zhirong, Gong, Tao, Peng, Qiang, Zhang, Qiang, Sun, Xun, Shi, Sanjun   +6 more
core   +1 more source

Development of Multi-Compartment 3D-Printed Tablets Loaded with Self-Nanoemulsified Formulations of Various Drugs: A New Strategy for Personalized Medicine

Pharmaceutics, 2021
This work aimed to develop a three-dimensional printed (3DP) tablet containing glimepiride (GLMP) and/or rosuvastatin (RSV) for treatment of dyslipidemia in patients with diabetes.
Tarek A. Ahmed, Raed I. Felimban, Hossam H. Tayeb, Waleed Y. Rizg, Fuad H. Alnadwi, Hanadi A. Alotaibi, Nabil A. Alhakamy, Fathy I. Abd-Allah, Gamal A. Mohamed, Ahmed S. Zidan, Khalid M. El-Say   +10 more
doaj   +1 more source

Optimization of a Beverage Using Mixture Design With Operational Variables

Journal of Engineering, Volume 2026, Issue 1, 2026.
The optimization of formulated products often requires simultaneous consideration of mixture composition and processing conditions, as both factors can strongly influence the final response. In this study, a mixture experimental design incorporating process variables was applied to the optimization of a prepared beverage (margarita), with the objective
Javier Cruz-Salgado, Sergio Alonso-Romero, Misaela Francisco Márquez, Uziel Mejía González, Himadri Majumder   +4 more
wiley   +1 more source

SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM- A NOVALAPPROACH FOR IMPROVING BIOAVAILABILITY

, 2014
The primary object of self-nanoemulsifying drug delivery system (SNEDDS) is to enhance the oral bioavailability of poorly  water soluble drugs.The major problem in oral formulations is low and erratic bioavailability, which mainly results due to poor ...
Gautam, Seema, Singh, Arun Kumar
core   +1 more source

Influences of Glimepiride Self-Nanoemulsifying Drug Delivery System Loaded Liquisolid Tablets on the Hypoglycemic Activity and Pancreatic Histopathological Changes in Streptozotocin-Induced Hyperglycemic Rats

Nanomaterials, 2022
The development of an oral anti-diabetic medication characterized by enhanced hypoglycemic activity is in high demand. The goal was to study the hypoglycemic activity and pancreatic histopathology after the black-seed-based self-nanoemulsifying drug ...
Tarek A. Ahmed, Hanadi A. Alotaibi, Alshaimaa M. Almehmady, Martin K. Safo, Khalid M. El-Say   +4 more
doaj   +1 more source

Current Therapeutic Strategies, Recent Advances and the Emerging Potential of Natural Products in Hepatocellular Carcinoma

Scientifica, Volume 2026, Issue 1, 2026.
Hepatocellular carcinoma (HCC) accounts for 75%–85% of all primary liver cancers and remains one of the leading causes of cancer‐related mortality worldwide. Despite advances in diagnosis and systemic therapies, the clinical management of HCC is hindered by limited therapeutic efficacy, drug resistance, systemic toxicity and high recurrence rates ...
Felix Wambua Muema, Catherine M. Miller, Lionel Hebbard, Phurpa Wangchuk, Asmat Ullah   +4 more
wiley   +1 more source

Development of 3D-Printed, Liquisolid and Directly Compressed Glimepiride Tablets, Loaded with Black Seed Oil Self-Nanoemulsifying Drug Delivery System: In Vitro and In Vivo Characterization

Pharmaceuticals, 2022
Glimepiride is characterized by an inconsistent dissolution and absorption profile due to its limited aqueous solubility. The aim of this study was to develop glimepiride tablets using three different manufacturing techniques, as well as to study their ...
Tarek A. Ahmed, Hanadi A. Alotaibi, Waleed S. Alharbi, Martin K. Safo, Khalid M. El-Say   +4 more
doaj   +1 more source