Results 71 to 80 of about 2,372,069 (151)

Myelin Impairment and Regeneration in the Central Nervous System: Molecular Mechanisms, Diseases, and Prospective Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
Proper myelin formation is crucial for normal neural circuit function, while myelin deficiency can lead to neural circuit dysfunction and cognitive decline, notably in Alzheimer's disease and other central nervous system demyelinating disorders. This review summarizes central myelin's structure and function, demyelination biomarkers and pathological ...
Lihong Huang, Peng Cheng, Guangdong Liu, Yang Xiang, Zhen Hong, Weidong Le   +5 more
wiley   +1 more source

Alveolar Macrophages: Development, Respiratory Homeostasis, Signal Pathways, Diseases, and Therapeutic Opportunities

MedComm, Volume 7, Issue 10, October 2026.
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang, Ruomeng Li, Chuanjiang Yu, Jing Li, Xikun Zhou   +4 more
wiley   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, Volume 38, Issue 51, 11 September 2026.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Specialized pro-resolving lipid mediators in gut immunophysiology: from dietary precursors to inflammation resolution. [PDF]

PURPOSE OF REVIEW: This review aims to examine recent research on the role of specialized pro-resolving mediators (SPMs) in the regulation of gut immunophysiology. RECENT FINDINGS: Inflammatory bowel disease (IBD) is characterized by chronic inflammation
Dalli, J, Albuquerque-Souza, E
core   +1 more source

Can Inflammation-Resolution Provide Clues to Treat Patients According to Their Plaque Phenotype?

Frontiers in Pharmacology, 2019
Inflammation-resolution is an active process that is governed in part by specialized pro-resolving mediators (SPMs) such as lipoxins, resolvins, protectins, and maresins.
Gabrielle Fredman
doaj   +1 more source

Specialized pro-resolving mediators in neutrophil apoptosis regulation: unlocking novel therapeutic potential in kidney diseases

Frontiers in Immunology
Kidney diseases represent a diverse group of disorders with pathogenic mechanisms involving multiple pathological processes, including inflammation, immunity, and cell death.
Yi Kang, Yi Kang, Yi Kang, Qian Jin, Mengqi Zhou, Huijuan Zheng, Huijuan Zheng, Danwen Li, Danwen Li, Danwen Li, Xuezhe Wang, Xuezhe Wang, Xuezhe Wang, Jingwei Zhou, Jingwei Zhou, Yaoxian Wang, Jie Lv   +16 more
doaj   +1 more source

DataSheet1_Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators—What is the Evidence so far?.PDF

, 2022
Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic acid 12- and 15-lipoxygenating paralogues (15-LO1, ALOX15; 15 ...
Astrid S. Kahnt (1373697), Karsten H. Weylandt (12176975), Robert C. Murphy (66787), Claes Dahlgren (21146), Nicolas Flamand (309143), Nadine Rohwer (244172), Nils Helge Schebb (803707), Gerd Geisslinger (109814), Per-Johan Jakobsson (356891), Dieter Steinhilber (182458), Hartmut Kühn (10732929), Mohamad Wessam Alnouri (12176978), Katharina M. Rund (6430874), Marc Peters-Golden (359881), Garret A. FitzGerald (165472), Valerie B. O’Donnell (6523538), Julien Hanson (2481121), Stefan Offermanns (223955)   +17 more
core   +1 more source

Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution

, 2020
Underlying mechanisms of how infectious inflammation is resolved by the host are incompletely understood. One hallmark of inflammation resolution is the activation of specialized pro-resolving mediators (SPMs) that enhance bacterial clearance and promote
Gerstmeier, Jana, Löffler, Bettina, Bilancia, Rossella, Börner, Friedemann, Serhan, Charles N, Jordan, Paul M, Miek, Laura, Ialenti, Armando, Rao, Zhigang, Rossi, Antonietta, Gutiérrez-Gutiérrez, Óscar, Arakandy, Vandana, González-Estévez, Cristina, Pace, Simona, Werz, Oliver, Tuchscherr, Lorena   +15 more
core   +2 more sources

Pro-resolving lipid mediator Resolvin D1 serves as a marker of lung disease in cystic fibrosis.

PLoS ONE, 2017
BackgroundCystic fibrosis (CF) is an autosomal recessive genetic disorder that affects multiple organs, including the lungs, pancreas, liver and intestine.
Olaf Eickmeier, Daniela Fussbroich, Klaus Mueller, Friederike Serve, Christina Smaczny, Stefan Zielen, Ralf Schubert   +6 more
doaj   +1 more source

E-series resolvin metabolome, biosynthesis and critical role of stereochemistry of specialized pro-resolving mediators (SPMs) in inflammation-resolution: Preparing SPMs for long COVID-19, human clinical trials, and targeted precision nutrition. [PDF]

Semin Immunol, 2022
Serhan CN, Libreros S, Nshimiyimana R.
europepmc   +1 more source