Effect of recombinant human vascular endothelial growth factor on testis tissue xenotransplants from prepubertal boys: a three-case study [PDF]
, 2019 Research question Does recombinant human vascular endothelial growth factor (VEGF-165) improve the efficiency of human immature testis tissue (ITT) xenotransplantation?
Goossens, Ellen +5 more
core +1 more source
Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]
, 2010 Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H. +4 more
core +2 more sources
Spermatogonial kinetics in humans [PDF]
, 2017 The human spermatogonial compartment is essential for daily production of millions of sperm. Despite this crucial role, the molecular signature, kinetic behavior and regulation of human spermatogonia are poorly understood.
Berloco, Bartolomeo P. +11 more
core +1 more source
Mammalian germ cell migration during development, growth, and homeostasis
Reproductive Medicine and Biology, 2019 Background Germ cells represent one of the typical cell types that moves over a long period of time and large distance within the animal body. To continue its life cycle, germ cells must migrate to spatially distinct locations for proper development ...
Mizuho Kanamori +3 more
doaj +1 more source
Frontiers in Endocrinology, 2017 Previous work showed that pharmacological inactivation of Igf-binding proteins (Igfbps), modulators of Igf activity, resulted in an excessive differentiation of type A undifferentiated (Aund) spermatogonia in zebrafish testis in tissue culture when Fsh ...
Diego Safian +5 more
doaj +1 more source
Developmental changes in the histological structure of the testes, and testosterone profiles in male guinea fowls (Numida meleagris) [PDF]
, 2017 Owing to the paucity of information on the reproductive biology of guinea fowls, a study involving a total of 66 males was conducted, and documented the developmental changes in histological structure of the testes of guinea cocks from hatching until ...
Abdul-Rahman, Iddriss I. +2 more
core +1 more source
Somatic ERK activation during transit amplification is essential for maintaining the synchrony of germline divisions in Drosophila testis [PDF]
Open Biology, 2018 Transit amplification (TA) of progenitor cells maintains tissue homeostasis by balancing proliferation and differentiation. In Drosophila testis, the germline proliferation is tightly regulated by factors present in both the germline and the neighbouring
Samir Gupta +3 more
doaj +1 more source
Assessing the Sensitivity of Different Life Stages for Sexual Disruption in Roach (Rutilus rutilus) Exposed to Effluents from Wastewater Treatment Works [PDF]
, 2005 Surveys of U.K. rivers have shown a high incidence of sexual disruption in populations of wild roach (Rutilus rutilus) living downstream from wastewater treatment works (WwTW), and the degree of intersex (gonads containing both male and female structural
Charles R. Tyler +8 more
core +2 more sources
Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch. [PDF]
, 2020 Male factor infertility is a problem in today's society but many underlying causes are still unknown. The generation of a conditional Sertoli cell (SC)-specific connexin 43 (Cx43) knockout mouse line (SCCx43KO) has provided a translational model ...
Behr, Rüdiger +10 more
core +1 more source
Cells, 2020 Filamins are large dimeric F-actin cross-linking proteins, crucial for the mechanosensitive properties of a number of cell types. Due to their interaction with a variety of different proteins, they exert important regulatory functions.
Harald Welter +8 more
doaj +1 more source