Results 61 to 70 of about 33,731 (224)

Long-Term Propagation of Porcine Undifferentiated Spermatogonia [PDF]

open access: yesStem Cells and Development, 2017
Spermatogonial stem cells (SSCs) provide the foundation for spermatogenesis and fertility throughout the adult life of a male. Genetic manipulations of SSCs combined with germ cell transplantation present a novel approach for gene therapy and production of genetically modified animals.
Zhang, Pengfei   +6 more
openaire   +3 more sources

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

open access: yesInterdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang   +6 more
wiley   +1 more source

Molecular Investigations on Angiogenesis and Oxidative Stress in Roe Deer (Capreolus capreolus) Bucks' Testes Throughout the Reproductive Cycle

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Animals with seasonal reproductive cycles, as the Roe deer (Capreolus capreolus), have developed mechanisms to synchronize reproduction with the environmental cycle in order to optimize reproductive success through melatonin. Angiogenesis and oxidative stress are key processes in spermatogenesis, contributing to testicular remodeling and ...
Ilaria Troisio   +7 more
wiley   +1 more source

Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice

open access: yesStem Cell Reports, 2017
The introduction of megabase-sized large DNA fragments into the germline has been a difficult task. Although microcell-mediated chromosome transfer into mouse embryonic stem cells (ESCs) allows the production of transchromosomic mice, ESCs have unstable ...
Takashi Shinohara   +12 more
doaj   +1 more source

Epigenetic Regulation of TET1-SP1 During Spermatogonia Self-Renewal and Proliferation

open access: yesFrontiers in Physiology, 2022
Spermatogonia are the source of spermatogenic waves. Abnormal spermatogonia can cause ab-normal spermatogenic waves, which manifest as spermatogenic disorders such as oligospermia, hypospermia, and azoospermia.
Lingling Liu   +5 more
doaj   +1 more source

Growth inhibition and morphologic changes of HeLa cells exposed to unsaturated fatty acid fraction from the liver of x-ray irradiated rabbits (OX) [PDF]

open access: yes, 1962
Biological effect of the unsaturated fatty acid fraction from the X-ray irradiated rabbit liver (OX) on HeLa cells has been observed in vitro comparing with the effect displayed on the same strain cells by the unsaturated fatty acid fraction from the non-
Seno, Satimaru   +2 more
core   +1 more source

Regulatory mechanisms of reproduction in locusts and grasshoppers

open access: yesNew Plant Protection, EarlyView.
Regulatory networks composed of numerous coding and noncoding genes play crucial roles in the reproduction of locusts and grasshoppers. This review integrates mechanistic advances in reproductive regulation, highlighting environmentally adaptive pathways and providing prospective targets for eco‐friendly pesticides.
Jing He, Jiliang Wang, Xinran Wang
wiley   +1 more source

Cracd Marks the First Wave of Meiosis during Spermatogenesis and Is Mis-Expressed in Azoospermia Mice

open access: yesJournal of Developmental Biology, 2020
Testicular development starts in utero and maturation continues postnatally, requiring a cascade of gene activation and differentiation into different cell types, with each cell type having its own specific function.
Paige L. Snider   +2 more
doaj   +1 more source

Prmt7 Downregulation in Mouse Spermatogonia Functions through miR-877-3p/Col6a3

open access: yesLife, 2022
Protein arginine methyltransferases 7 (Prmt7) is expressed in male germ cells, including primordial germ cells, gonocytes, and spermatogonia. Our previous study demonstrated that Prmt7 downregulation reduced the proliferation of GC-1 cells (a cell line ...
Hongmei Gao   +6 more
doaj   +1 more source

Macrophages in endocrine glands, with emphasis on pancreatic islets [PDF]

open access: yes, 2016
We review here the macrophages found in endocrine tissues, placing emphasis on those residing in the islets of Langerhans of the pancreas. The islets represent the endocrine organ where macrophages have been examined in great detail and where our own ...
Unanue, Emil R
core   +2 more sources

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