Results 71 to 80 of about 33,731 (224)

TALEN‐mediated gene targeting in porcine spermatogonia [PDF]

Molecular Reproduction and Development, 2018
Spermatogonia represent a diploid germ cell population that includes spermatogonial stem cells. In this report, we describe new methods for isolation of highly enriched porcine spermatogonia based on light scatter properties, and for targeted mutagenesis in porcine spermatogonia using nucleofection and TALENs.
Lin Tang, Alla Bondareva, Raquel González, Jose R. Rodriguez‐Sosa, Daniel F. Carlson, Dennis Webster, Scott Fahrenkrug, Ina Dobrinski   +7 more
openaire   +2 more sources

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Selenoproteins in mammalian spermatogenesis:role of the nuclear GPx4 [PDF]

, 2011
The selenoprotein Phospholipid Hydroperoxide Glutathione Peroxidase (PHGPx/GPx4) is an enzyme unique among the various GPxs, because it is able to use protein thiols, beside glutathione, The GPx4 gene encodes for three isoforms having different ...
Maccari, Irene
core  

Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis [PDF]

, 2010
Meiosis is unique to germ cells and essential for reproduction. During the first meiotic division, homologous chromosomes pair, recombine, and form chiasmata.
Choi, Y, Erdin, SU, Kloc, M, Meistrich, ML, Rajkovic, A, Shin, YH, Wang, PJ, Yang, F, Yatsenko, SA   +8 more
core   +5 more sources

Cell Cycle of Spermatogonia in Mouse Testis [PDF]

Investigative Radiology, 1979
This report measures the spermatogonial cell cycles and their constituent phases of proliferating type A, intermediate (In), and type B cells in the testis of the young mouse, and analyzes the cell cycle and cell population kinetic parameters, such as growth fractions and cell-birth rates, from /sup 3/HTdR autoradiographic data.
openaire   +3 more sources

Spermatogonia Differentiation Requires Retinoic Acid Receptor γ [PDF]

Endocrinology, 2012
Vitamin A is instrumental to mammalian reproduction. Its metabolite, retinoic acid (RA), acts in a hormone-like manner through binding to and activating three nuclear receptor isotypes, RA receptor (RAR)α (RARA), RARβ, and RARγ (RARG). Here, we show that 1) RARG is expressed by A aligned (Aal) spermatogonia, as well as during the transition from Aal to
Gely-Pernot, Aurore, Raverdeau, Mathilde, Celebi, Catherine, Dennefeld, Christine, Féret, Betty, Klopfenstein, Muriel, Yoshida, Shosei, Ghyselinck, Norbert, Mark, Manuel   +8 more
openaire   +2 more sources

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

The effect of immobilization stress on the HPG axis (hypothalamic - pituitary - gonad) hormones and the number of spermatogonia [PDF]

Journal of Advanced Biomedical Sciences, 2013
Background & Objective: Stress has different effects on the living organisms. In this study the effect of immobilization stress the HPG (hypothalamic - pituitary - gonad axis) hormones secretion and the number of spermatogonia was studied in adult male ...
ahmad mozafar, mojtaba keshavarz, parvin zareian, Habiboalah Johary, hossein kargar jahromy, Shirzad Hoseini   +5 more
doaj  

Presence and localization of a 30-kDa basic fibroblast growth factor-like protein in rodent testes [PDF]

, 1991
We have used a recently characterized rabbit antiserum against basic fibroblast growth factor (bFGF), which recognizes various forms of bFGF, to examine the presence and localization of bFGF in the testes of adult rats and mice and the 5-day-old rat.
Gratzl, Manfred, Grothe, C., Mayerhofer, Artur, Rudolf, M., Russell, J. T.   +4 more
core   +1 more source

Pharmacogenetics of follicle‐stimulating hormone action in the male

Andrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani, Giuseppe Grande, Raffele Scafa, Riccardo Selice, Andrea Garolla, Maria Santa Rocca, Cinzia Vinanzi, Alberto Ferlin   +7 more
wiley   +1 more source