Results 11 to 20 of about 23,772 (188)

L-ornithine derived polyamines in cystic fibrosis airways. [PDF]

PLoS ONE, 2012
Increased arginase activity contributes to airway nitric oxide (NO) deficiency in cystic fibrosis (CF). Whether down-stream products of arginase activity contribute to CF lung disease is currently unknown.
Hartmut Grasemann, Darakhshanda Shehnaz, Masahiro Enomoto, Michael Leadley, Jaques Belik, Felix Ratjen   +5 more
doaj   +1 more source

Effects of dietary spermine supplementation on cell cycle, apoptosis, and amino acid transporters of the thymus and spleen in piglets [PDF]

Asian-Australasian Journal of Animal Sciences, 2018
Objective This study investigated whether spermine supplementation could regulate cell cycle, apoptosis, and amino acid transporter-related genes expression in the thymus and spleen of early weaned piglets.
Wei Cao, Xianjian Wu, Gang Jia, Hua Zhao, Xiaoling Chen, Caimei Wu, Jingyi Cai, Jing Wang, Guangmang Liu   +8 more
doaj   +1 more source

The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis

Frontiers in Plant Science, 2015
In Arabidopsis three basic region leucine zipper (bZIP) transcription factor genes, bZIP17, bZIP28 and bZIP60, play crucial roles in the unfolded protein response (UPR). Previously we found that bZIP60 is one of the spermine-induces genes.
G.H.M. eSagor, Pratima eChawla, Dong Wook eKim, Thomas eBerberich, Seiji eKojima, Masaru eNiitsu, Tomonobu eKusano   +6 more
doaj   +1 more source

Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer

Cell Reports, 2023
Summary: In castration-resistant prostate cancer (CRPC), clinical response to androgen receptor (AR) antagonists is limited mainly due to AR-variants expression and restored AR signaling.
Xiao Li, Fei Li, Fei Ye, Haotian Guo, Wentao Chen, Jia Jin, Yiran Wang, Pengfei Dai, Huili Shi, Hongru Tao, Wenzhen Dang, Yiluan Ding, Mingchen Wang, Hualiang Jiang, Kaixian Chen, Naixia Zhang, Dong Gao, Yuanyuan Zhang, Cheng Luo   +18 more
doaj   +1 more source

Effects of spermine supplementation on the morphology, digestive enzyme activities, and antioxidant capacity of intestine in weaning rats

Animal Nutrition, 2016
The main objective of this study was to investigate the effects of different doses of spermine and its extended supplementation on the morphology, digestive enzyme activities, and intestinal antioxidant capacity in weaning rats.
Tingting Fang, Gang Jia, Hua Zhao, Xiaoling Chen, Jiayong Tang, Jing Wang, Guangmang Liu   +6 more
doaj   +1 more source

Application of the "Plazmontest" Software and Hardware Complex for the Determination of Spermine Concentration

Кібернетика та комп'ютерні технології, 2023
Introduction. One of the main areas of application of SPR sensors is biochemical analysis. The "Plasmontest" device, developed at the Institute of Cybernetics of the National Academy of Sciences of Ukraine, was used for rapid diagnosis of various ...
Tetyana Lebyedyeva, Yuriy Minov, Maksym Prylutskyi, Pavlo Sutkovyi, Yurii Frolov, Pavlo Shpylovyy   +5 more
doaj   +1 more source

A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury.

PLoS ONE, 2013
Spermine oxidase is a FAD-containing enzyme involved in polyamines catabolism, selectively oxidizing spermine to produce H2O2, spermidine, and 3-aminopropanal. Spermine oxidase is highly expressed in the mouse brain and plays a key role in regulating the
Manuela Cervelli, Gabriella Bellavia, Marcello D'Amelio, Virve Cavallucci, Sandra Moreno, Joachim Berger, Roberta Nardacci, Manuela Marcoli, Guido Maura, Mauro Piacentini, Roberto Amendola, Francesco Cecconi, Paolo Mariottini   +12 more
doaj   +1 more source

Improving Chilling Tolerance of Maize Seedlings under Cold Conditions by Spermine Application

Notulae Scientia Biologicae, 2012
Low temperature is an important abiotic stress which reduces crops growth and productivity and causes physiological damages to cellular structures. The aim of this study was to investigate the probability of spermine application to improve chilling ...
Amir Hossein SAEIDNEJAD, Farzin POURAMIR, Mahdi NAGHIZADEH   +2 more
doaj   +3 more sources

Changes in the sugars, amino acids and organic acids of postharvest spermine-treated immature vegetable soybean (Glycine max L. Merr.) as determined by 1H NMR spectroscopy

Food Production, Processing and Nutrition, 2020
1H NMR spectroscopy was adopted to determine compositional changes (mainly sugars, organic acids and amino acids) involved in cold-stored immature soybean grains after exogenous spermine treatment.
Jiangfeng Song, Gang Wu, Tao Li, Chunquan Liu, Dajing Li   +4 more
doaj   +1 more source

The Involvement of Polyamines Catabolism in the Crosstalk between Neurons and Astrocytes in Neurodegeneration

Biomedicines, 2022
In mammalian cells, the content of polyamines is tightly regulated. Polyamines, including spermine, spermidine and putrescine, are involved in many cellular processes. Spermine oxidase specifically oxidizes spermine, and its deregulated activity has been
Manuela Cervelli, Monica Averna, Laura Vergani, Marco Pedrazzi, Sarah Amato, Cristian Fiorucci, Marianna Nicoletta Rossi, Guido Maura, Paolo Mariottini, Chiara Cervetto, Manuela Marcoli   +10 more
doaj   +1 more source