Results 81 to 90 of about 27,012 (233)

Polyamine metabolism changes in psoriasis

Indian Journal of Dermatology, 2013
Introduction: Polyamines - putrescine, spermidine and spermine are polycationic compounds ubiquitous for all living organisms. They are essential for the cell growth and differentiation, the control of cell cycle progress, apoptosis, and cancerogenesis ...
Valentina Broshtilova, Valentina Lozanov, Ljubka Miteva   +2 more
doaj   +1 more source

Fluorinated analogues of spermidine as substrates of spermine synthase [PDF]

, 1988
Jean Baillon, Pierre S. Mamont, Joseph E. Wagner, F. Gerhart, Philippe Lux   +4 more
openalex   +1 more source

Nanoparticle‐Mediated Delivery of Adenosine 5′‐Monophosphate Enhances 5‐Oxoprolinase Activity to Mitigate Oxidative Stress in Heart Failure

Advanced Therapeutics, Volume 9, Issue 1, January 2026.
Researchers establish a high‐throughput screening technique that identifies adenosine 5′‐monophosphate as a novel activator of 5‐oxoprolinase (OPLAH). To enhance cellular permeability, they employ spermine‐modified acetalated dextran nanoparticles for effective intracellular delivery.
Antonio Esquivel‐Gaytan, Nils Bomer, Raquel Bartolo, Karla F. Arevalo‐Gomez, Frederik E. Deiman, Maaike Bras, Saman Honarnejad, Hjalmar Permentier, Alexander Dömling, Adriaan A. Voors, Hélder A. Santos, Herman H. W. Silljé, Peter Van der Meer   +12 more
wiley   +1 more source

A mutation at AP2 locus of Arabidopsis confers spermine resistance [PDF]

, 1997
Javed Iqbal Mirza, Hamid Saeed
openalex   +1 more source

Molecular mechanisms of spermine on its synergistic effect with beta-lactams against Staphylococcus aureus

, 2022
Xiangyu Yao
openalex   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, Volume 13, Issue 2, 9 January 2026.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

Spermine driven water deficit tolerance in early growth phases of sweet corn genotypes under hydroponic cultivation

Scientific Reports
Sweet corn is highly susceptible to water deprivation, making it crucial to identify effective strategies for enhancing its tolerance to water deficit conditions.
Tahoora Batool Zargar, Mawia Sobh, Oqba Basal, Tibor Janda, Magda Pál, Szilvia Veres   +5 more
doaj   +1 more source

Heterologous Expression and Characterization of Mouse Spermine Oxidase [PDF]

, 2003
Manuela Cervelli, Fabio Polticelli, Rodolfo Federico, Paolo Mariottini   +3 more
openalex   +1 more source

A Pan‐TE Map Reveals the Important Role of Transposable Elements in Gene Expression and Phenotypic Diversity in 2,311 Rapeseed Accessions

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study presents the first pan‐transposable element (TE) atlas in rapeseed, profiling over 8 million TEs across 2311 accessions. Integrative analyses reveal that TEs broadly shape gene expression through diverse regulatory mechanisms, with key insertions in BnaA03.FLC and BnaA09.CYP78A9 linked to flowering time and silique development.
Zhiquan Yang, Haiyan Fan, Yifan Chen, Jiawei Li, Minjian Chen, Yingying Tan, Liang Guo, Jintao Li, Kede Liu, Qing‐Yong Yang   +9 more
wiley   +1 more source

Arid1a Deficiency Drives Aristolochic Acid‐Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair

Advanced Science, Volume 13, Issue 3, 14 January 2026.
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang, Shi‐Hao Bai, Shu‐Jin Song, Xiao‐Li Zhang, Xue‐Ying Shang, Zhao‐Ning Lu, Xiao‐Fang Cui, Xin‐Le Zhu, Ze‐Guang Han   +8 more
wiley   +1 more source