Results 1 to 10 of about 50,070 (158)

Role of the transmembrane domain in severe acute respiratory syndrome (SARS) coronavirus 2 spike for palmitoylation and membrane fusion. [PDF]

Protein Sci
Abstract Palmitoylation is a reversible post‐translational modification that enhances protein hydrophobicity and regulates cellular functions such as trafficking and signaling. In humans, this modification is catalyzed by 23 DHHC enzymes, but the mechanisms by which they recognize their substrates remain unclear.
Abdulrahman DA, Veit M.
europepmc   +2 more sources

Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay. [PDF]

, 2011
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) emerged as the causal agent of an endemic atypical pneumonia, infecting thousands of people worldwide.
Agudelo, Juliet, Amberg, Sean M, Chen, Yen Ting, Craik, Charles S, Goetz, David H, Hansell, Elizabeth, Lu, Kai, McKerrow, James, Roush, William R, Simmons, Graham, Zhou, Yanchen   +10 more
core   +1 more source

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes [PDF]

, 2012
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs.
A. Vabret, Abt, Arbour, Arbour, B. Nal, Bonavia, Caignard, Caignard, Callendret, Callow, Caux, Chapuis, Collins, de Swart, de Witte, Desforges, Desforges, Engelmayer, Esposito, F. Tangy, Ferlazzo, Gagneur, Geijtenbeek, Glew, H. Law, Hahm, Hamdorf, Herbst, Hoarau, J. Millet, Kramer, Kärber, Law, Legge, M. L. Albert, M. Mesel-Lemoine, MacDonald, Mahanty, Movassagh, Muller, N. Escriou, Nogueira, O'Doherty, Olweus, P.-O. Vidalain, Pacanowski, Piqueras, Rosenzwajg, Sallusto, Servet-Delprat, Servet-Delprat, Servet-Delprat, Sizun, Spearman, Spiegel, Thitithanyanont, Thornberry, V. Lorin, Vabret, Wang, Yang, Yeager   +61 more
core   +3 more sources

Ezrin interacts with the SARS coronavirus spike protein and restrains infection at the entry stage [PDF]

, 2012
© 2012 Millet et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Chen, A Roumier, AG Wise, B Fievet, B Nal, B Treanor, B Treanor, BJ Bosch, BT Fievet, Béatrice Nal, C Drosten, CE McBride, CE McBride, Chung-Yan Cheung, CM Finnerty, CM Petit, CM Petit, CY Cheung, D Cavanagh, E Formstecher, E Lontok, François Kien, G Simmons, G Simmons, H Ma, Hiu-Lan Leung, HS Kim, Huiying Li, I Nefkens, IC Huang, J Haedicke, Jean Kaoru Millet, JK Locker, Joseph S. Malik Peiris, JP Nuesch, JP Richard, JS Peiris, K Hamada, K Hamada, KT Teoh, L Naldini, M Algrain, M Barrero-Villar, M Baumgartner, M Fromont-Racine, M Jaume, Martial Jaume, MH Naghavi, MJ Moore, MW Howard, N Gupta, P Wang, PC Woo, PC Woo, R Lasserre, R Zufferey, Ralf Marius Altmeyer, RG Fehon, RI Connor, Roberto Bruzzone, S Charrin, S Yonemura, SF Altschul, SK Lau, Stefan Pöhlmann, T Crepaldi, T Giroglou, T Kuiken, T Mori, TG Ksiazek, V Das, W Li, Wing-Lim Chan, WJ Smith, Y Kubo, YJ Zhang, YL Siu, Yu-Lam Siu, YW Kam, YW Kam   +79 more
core   +6 more sources

Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China. [PDF]

, 2020
On 10 January 2020, a new coronavirus causing a pneumonia outbreak in Wuhan City in central China was denoted as 2019-nCoV by the World Health Organization (WHO).
Du, Lanying, Jiang, Shibo, Ojcius, David M, Pan, Chungen, Yu, Fei   +4 more
core   +1 more source

The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles [PDF]

, 2008
Copyright @ 2008 American Society for Microbiology.The production of virus-like particles (VLPs) constitutes a relevant and safe model to study molecular determinants of virion egress.
Altmeyer, R, Bruzzone, R, Chan, CM, Escriou, N, Kien, F, Lo, J, Nal, B, Nicholls, JM, Peiris, JSM, Siu, YL, Teoh, KT, Tsao, SW   +11 more
core   +5 more sources

An optimised method for the production of MERS-CoV spike expressing viral pseudotypes [PDF]

, 2015
The production and use of pseudotyped viral particles is widely established for many viruses, and applications in the fields of serology and vaccine development are manifold.
Carnell, Ferrara, Kutner, Mather, Molesti, Qian, Scott, Temperton, Wang, Zhao, Zufferey, Zufferey   +11 more
core   +2 more sources

Molecular aspects of MERS-CoV [PDF]

, 2017
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Ahmed, Shamsah H., Al-Tawfiq, Jaffar A., Bazzi, Ali M., Rabaan, Ali A.   +3 more
core   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelination. [PDF]

, 2014
BackgroundFTY720 (fingolimod) is the first oral drug approved by the Food and Drug Administration for treatment of patients with the relapsing-remitting form of the human demyelinating disease multiple sclerosis.
Blanc, Caroline A, Lane, Thomas E, Rosen, Hugh   +2 more
core   +1 more source